Following heart changes in young competitive endurance athletes over time
Observes how training and genes affect heart changes in young endurance athletes.
Plain-language title generated from the registry record
Registry title: Prospective Athlete's Heart Study
Key facts
- Where
- Melbourne, AustraliaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for young endurance athletes aged 14-23 years, and for non-athletes who are physically active less than 3 hours per week.
- Age
- 14 to 23 years
- Sex
- Men and women
Main reasons for not taking part
- History of heart or blood vessel disease
- Currently smokes, or has smoked in the past
- Diabetes mellitus
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 14 and 23 years old?
Source: NCT05164328, who can take part
Where in Australia
- Baker Heart and Diabetes InstituteMelbourne, AustraliaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universitaire Ziekenhuizen KU Leuven
- Trial code
- NCT05164328
- Record updated
- 20 December 2021
- Original description
The Pro@Heart (Prospective Athlete's Heart) study is an international multicentre long-term prospective trial. The primary objective of the Pro@Heart study is to investigate the impact of training load (i.e. accurately evaluated in term of type, frequency, duration and intensity) and genotype on the variability of structural, functional and electrical exercise induced cardiac remodeling (EICR) in young competitive endurance athletes. The second objective is to determine how EICR, training load and genotype are associated with physical performance, health benefits and cardiac pathology (e.g. exercise-related cardiomyopathies and arrhythmias) during follow-up over several decades.Read full original descriptionShow less
Prospective Athlete's Heart Study: Long-term Assessment of the Determinants of Cardiac Remodelling and Its Clinical Consequences in Endurance Athletes
The Pro@Heart (Prospective Athlete's Heart) study is an international multicentre long-term prospective trial. The primary objective of the Pro@Heart study is to investigate the impact of training load (i.e. accurately evaluated in term of type, frequency, duration and intensity) and genotype on the variability of structural, functional and electrical exercise induced cardiac remodeling (EICR) in young competitive endurance athletes. The second objective is to determine how EICR, training load and genotype are associated with physical performance, health benefits and cardiac pathology (e.g. exercise-related cardiomyopathies and arrhythmias) during follow-up over several decades.
Inclusion: Males and females aged 14-23 years old; Athletes competing in endurance sports at national or international level for at least 2 years. Sports include:; Triathlon; Cycling; Distance running (≥ 1500 meters); Rowing; Swimming; Non athletes engaged in < 3 hours per week of physical activity.
Exclusion: Medical history of cardiovascular disease; Current smoker of past history of smoking; Diabetes mellitus.