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NCT05169502Completed

Discovering Early Biomarkers in Circulating Endothelial Cells for Diabetes Complications by Single Cell RNA Sequencing

Identification of Biomarkers for Early Detection of Diabetes Complications by Characterisation of Circulating Endothelial Cells in Human Blood Using Single-cell RNA Sequencing.

Source: ClinicalTrials.gov · Last updated 20 Aug 2024

Brief summary (registry, in English)

The purpose of this study is to discover early biomarkers in circulating endothelial cells for diabetes complications, by investigating circulating endothelial cells in blood samples from patients with newly diagnosed proliferative diabetic retinopathy, newly diagnosed maculopathy, patients with diabetes without eye diseases, and individuals without diabetes by single-cell RNA sequencing. The single-cell RNA sequencing analysis will make it possible to fully phenotype diabetes circulating endothelial cells at single-cell level and reveal the first atlas of circulating endothelial cells in humans at both healthy and diabetes conditions.

Status (registry)
Completed
Study type
Observational
Enrollment
40 (actual)
First submitted
24 Nov 2021
Start date
8 Dec 2021
Primary completion date
1 Aug 2024
Lead sponsor
Aarhus University Hospital
NCT number
NCT05169502

What you commit to

  • Study type: Observational
  • Participants enrolled: 40
  • From 8 Dec 2021 to the primary completion date, 1 Aug 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Age \< 18 years

Other

  • Incapacitated

Who the study is looking for

  • Type I or II diabetes
  • Habile
  • Age\> 18 years

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Steno Diabetes Center Aarhus, Aarhus University Hospiral
Coordinator of this site? Confirm its status
AarhusDenmarkUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.