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Tracking care and outcomes of adults with cardiogenic shock at specialized hospitals

Follows adults with cardiogenic shock to learn how care and recovery unfold.

Plain-language title generated from the registry record
Registry title: Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

Key facts

Where
Toronto, CanadaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The registry is looking for adults whose main diagnosis is cardiogenic shock, a state where the heart cannot pump enough blood. It follows their care and outcomes at four shock care centers.

Age
18 Years and older
Sex
All sexes can join.
Disease stage
Cardiogenic shock as the main diagnosis at the first evaluation. This includes shock after a heart attack and shock from worsening heart failure. People with cardiac arrest during cardiogenic shock, or massive pulmonary embolism with right ventricle shock, can also join.

Main reasons for not taking part

  • Shock that does not come mainly from the heart
  • Septic shock (from infection)
  • Hemorrhagic shock (from blood loss)
  • Anaphylactic shock (from a severe allergic reaction)

Read by machine on 9 November 2026.

Where in Canada

  • University of TorontoToronto, CanadaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
STAVROS G DRAKOS
Trial code
NCT05185492
Record updated
20 March 2026
Original description
This large real-world international prospective registry will provide a unique opportunity to comprehensively understand the contemporary management, clinical course and short as well as long-term outcomes of all Cardiogenic Shock (CS) patients cared for at four high volume dedicated shock care centers. As the first true North American multicenter CS collaborative with a uniform dedicated and comprehensive case report form, the high patient volumes and wide spectrum of clinical acuity seen at these institutions will provide valuable insight into the factors associated with adverse outcomes; and will serve as a blueprint for future clinical trial designs that may better inform clinical practice.Read full original descriptionShow less

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

This large real-world international prospective registry will provide a unique opportunity to comprehensively understand the contemporary management, clinical course and short as well as long-term outcomes of all Cardiogenic Shock (CS) patients cared for at four high volume dedicated shock care centers. As the first true North American multicenter CS collaborative with a uniform dedicated and comprehensive case report form, the high patient volumes and wide spectrum of clinical acuity seen at these institutions will provide valuable insight into the factors associated with adverse outcomes; and will serve as a blueprint for future clinical trial designs that may better inform clinical practice.

Inclusion: Primary diagnosis of cardiogenic shock at time of index evaluation; including acute myocardial infarction- and acute decompensated heart failure-cardiogenic shock phenotypes; Patients with cardiac arrest complicating cardiogenic shock and those with massive pulmonary embolism with right ventricular cardiogenic shock will also be eligible for the registry.

Exclusion: Patients with shock not due to primary cardiac etiology will be excluded. These include septic, hemorrhagic, and anaphylactic shock.

ClinicalTrials.gov NCT05185492