Ibuprofen Versus Ketorolac for Pain Relief During Hysterosalpingogram
Key facts
- Who runs it
- Madigan Army Medical Center
- Where
- Tacoma, United StatesSee the site
- Trial code
- Status
- Terminated
- Phase
- Phase 4
- People taking part
- 12 people enrolled
- Started
- 24 Mar 2022
- Ended
- 10 Oct 2024
- Type of study
- Interventional, 2 groups
- Treatments tested
- Ibuprofen 800 mg oral
- Ketorolac 30mg oral
- Record updated
- 24 December 2024
- Why it stopped
- IRB voted to terminate the protocol for noncompliance
Who can take part
- Age
- 18 years to 45 years
- Sex
- Women only
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 16 criteriaShow less
Who can take part
- English speaking
- premenopausal females age 18-45
- patients currently undergoing HSG as part of routine work-up for infertility or subfertility, - - patients with negative urine pregnancy test within 24 hours of the scheduled procedure
- patients having performance of HCG between menstrual cycle days 5-12n
Who cannot take part
- patients with history of previous HSG performed
- use of pain medications within 12 hours of the scheduled procedure
- patients with contrast allergy or other contraindications to HSG
- active renal or hepatic disease
- patients with chronic pain conditions (fibromyalgia, complex regional pain syndrome, etc.)
- Non-English speaking
- patients with contraindications to NSAID use
- Patients with the following:
- unwilling to consent
- positive urine pregnancy test within 24 hours of the scheduled procedure
- chronic narcotic users
- patients with unknown uterine anatomical pathology
Where in United States
- Madigan Army Medical CenterTacoma, United States
About the trial
What the trial wants to find out
Hysterosalpingogram (HSG) testing is a vital part of the workup for infertility patients. It is often noted to be biggest pain that patients undergo during the workup. Several studies have attempted to find a therapy that reduces pain, with non-steroidal anti-inflammatory drugs such as oral ibuprofen the current mainstay. Our study attempts to determine which of the following NSAIDS is best at reducing pain associated with the HSG procedure: oral ibuprofen versus oral ketorolac .
The 2 groups in the trial
- IbuprofenTreatment being tested
Patients randomized to this arm will receive an identical capsule to the other patient arm, and receive 800mg ibuprofen 1 hour before HSG.
Treatment: Ibuprofen 800 mg oral
- KetorolacTreatment being tested
Patients randomized to this arm will receive an identical capsule to the other patient arm, and receive 30mg ketorolac 1 hour before HSG.
Treatment: Ketorolac 30mg oral
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 24 December 2024