Transcutaneous Oxygen Pressure (TcPO2) Determination.
Key facts
- Who runs it
- Hospices Civils de Lyon
- Where
- France1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 39 people enrolled
- Started
- 1 Mar 2022
- Ended
- 22 Jul 2025
- Type of study
- Observational, 2 groups
- Treatments tested
- TcPO2 measurement on the upper limb
- Record updated
- 8 May 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- healthy volunteer without upper limb arterial disease
- absence of opposition
- affiliated to social insurance
- patients with a TCPO2 measurement available for the upper limb
- patients with a follow-up of at least 3 months available
- absence of opposition
- affiliated to social insurance
Who cannot take part
- under 18 yrs old
- under law protection
- pregnancy; Retrospective patients part:
- under 18 yrs old
- under law protection
- pregnancy
Other criteria
- Healthy volunteers part:
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Upper limb arterial disease is a rare condition compared to lower limb arterial disease. In the lower limb, chronic limb ischemia (CLI) is characterized by an intractable pain or an ulceration present for at least 2 weeks. Guidelines recommend to use Transcutaneous Oxygen pressure (TcPO2) measurement when a CLI is suspected to establish diagnostic with a threshold of 30 mmHg when ankle and toe systolic pressure are not available.
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In the upper limb, there is no guideline to define CLI. When there is a wound preventing finger pressure measurement, TcPO2 is theoretically indicated. However, there is neither standardized site to measure nor threshold value of TcPO2.
The investigators hypothesized that normal TcPO2 may be different in the upper limb and that threshold value for CLI may also be different compared to lower limb.
The investigators planned a study with two parts:
1. Prospective study of normal TcPO2 value in healthy volunteers 2. Retrospective analysis of patients with upper limb arterial disease to approach the TcPO2 threshold of CLI allowing healing in upper limb
The 2 groups in the trial
- Healthy Volunteers
TcPO2 measurement in the upper limb of healthy volunteers
Treatment: TcPO2 measurement on the upper limb
- Patients with arterial disease in the upper limb and wound
Patients with arterial disease in the upper limb and wound (retrospective setting, research on data)
Treatment: TcPO2 measurement on the upper limb
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Standardized Transcutaneous Oxygen Pressure Determination in the Upper Limb: Normal Value and Chronic Limb Ischemia
- Record updated
- 8 May 2026