How the brain processes language, studied in people with epilepsy
Studies brain activity during language tasks in adults with epilepsy.
Plain-language title generated from the registry record
Registry title: Computational Neuroscience of Language Processing in the Human Brain
Key facts
- Where
- Boston, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT05222594, who can take part
Where in United States
- Massachusetts General HospitalBoston, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Massachusetts General Hospital
- Trial code
- NCT05222594
- Record updated
- 7 May 2026
- Original description
Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light on the construction and understanding of speech.Read full original descriptionShow less
Computational Neuroscience of Language Processing in the Human Brain
Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light on the construction and understanding of speech.
Inclusion: clinical indications to proceed with intracranial monitoring involving the left cerebral hemisphere, as determined by a multidisciplinary epilepsy surgery team; the ability to comply with test directions and provide informed consent; between ages 18 - 85.
Exclusion: inability to understand or perform the task outlined in the protocol, or who are unwilling or unable to participate.