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Taking people in FranceNo phase

Studying lung cells in smokers with and without COPD during cancer surgery

Studies lung cell repair in smokers with and without COPD, using tissue from surgery.

Plain-language title generated from the registry record
Registry title: Mapping and Characterization of Alveolar Cells During Smoking and Chronic Obstructive Disease

Key facts

Where
Créteil and Paris, FranceSee the 4 sites

Where in France

  • Rousseau-BussacCréteil, FranceTaking people
  • HEGPParis, FranceNo longer taking part
  • Hôpital CochinParis, FranceNo longer taking part
  • Hôpital TenonParis, FranceNo longer taking part

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  4. What happens if I want to stop?
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Trial details

Who runs it
Centre Hospitalier Intercommunal Creteil
Trial code
NCT05227547
Record updated
2 September 2025
Original description
To evaluate the regenerative capacities of mesenchymal cells composing the microenvironment of alveolar type 2 cells in a population of patients, undergoing thoracic surgery for suspected cancer, who are smokers with and without COPD compared to non-smokers patientsRead full original descriptionShow less

Mapping and Characterization of Alveolar Cells During Smoking and Chronic Obstructive Disease

To evaluate the regenerative capacities of mesenchymal cells composing the microenvironment of alveolar type 2 cells in a population of patients, undergoing thoracic surgery for suspected cancer, who are smokers with and without COPD compared to non-smokers patients

Inclusion: Age ≥ 18; Patient undergoing lung resection surgery (lobectomy, pneumonectomy, segmentectomy) for cancer or suspected cancer; Acceptance to participate in the protocol; Affiliated to a social security plan.

Exclusion: Neo-adjuvant chemotherapy; Chronic autoimmune disease; History of thoracic radiotherapy; Patient under guardianship or curators; Pregnant woman; Minor patient; Person not able to consent; Person deprived of liberty.

ClinicalTrials.gov NCT05227547