Ganciclovir Resistant/Refractory Cytomegalovirus Infection in SOT Recipients and HSCT Patients
Key facts
- Where
- Brussels and Leuven, BelgiumSee the 2 sites
Where in Belgium
- Institut Jules BordetBrussels, BelgiumContact: Angela LoizidouNot yet recruiting
- University Hospitals LeuvenLeuven, BelgiumContact: Laurent GodinasNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Trial code
- NCT05234723
- Record updated
- 15 June 2026
- Original description
The ReCySOHT study is a multicenter, retrospective, observational case-control study on the risk factors for developing a ganciclovir-resistant/refractory (GCV-RR) cytomegalovirus infection in patients receiving solid organ transplant (SOT) or hematopoietic stem cell transplant (HSCT). Aims of the study are to investigate the incidence of and risk factors for GCV-RR CMV infection in SOT recipients and HSCT patients in order to design further studies aimed at preventing and improving the patient management of GCV-RR CMV infections.Read full original descriptionShow less
Epidemiological Burden of and Risk Factors for Ganciclovir Resistant/Refractory Cytomegalovirus in Solid Organ Transplant and Hematopoietic Stem Cell Transplant Patients: Multicentre Cohort Study
The ReCySOHT study is a multicenter, retrospective, observational case-control study on the risk factors for developing a ganciclovir-resistant/refractory (GCV-RR) cytomegalovirus infection in patients receiving solid organ transplant (SOT) or hematopoietic stem cell transplant (HSCT). Aims of the study are to investigate the incidence of and risk factors for GCV-RR CMV infection in SOT recipients and HSCT patients in order to design further studies aimed at preventing and improving the patient management of GCV-RR CMV infections.
Inclusion: All adult (≥ 18 years) patients who underwent SOT or HSCT developing CMV-infection treated with GC/VGC; Ability to understand the purpose of the study and provide signed and dated informed consent.
Exclusion: Lack of the serological mismatch at transplantation; Lack of clinical and/or laboratory data regarding the type of CMV event; Lack of the type of SOT or HSCT; Lack of the patient and graft outcome at 30, 60 or 90 days after CMV event diagnosis.