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Testing brain stimulation with mirror therapy for stroke recovery

Tests a brain stimulation device with mirror therapy in adults recovering from stroke.

Plain-language title generated from the registry record
Registry title: Novel Brain Neurotechnology for Optimizing Precision Mirror Therapy in Stroke

Key facts

Where
Taoyuan, TaiwanSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 35 to 85 who had a first stroke on one side at least 3 months ago and have mild to moderate arm weakness.

Age
35 to 85 years
Sex
All sexes can join.
Disease stage
First-ever stroke on one side of the brain, at least 3 months ago, with moderate to mild arm movement problems (FMA score 18 to 56) and no excessive spasticity in the affected arm.
Earlier treatment
Cannot have had botulinum toxin injections in the 3 months before joining. Cannot be taking part in other rehabilitation experiments or drug trials.
Biomarker or test result
Mini Mental State Examination score of 24 or more, so the person can follow instructions.

Main reasons for not taking part

  • History of epilepsy
  • Pregnant
  • Pacemaker or metal implants in the neck or head
  • History of drug or alcohol abuse
  • Other brain conditions such as dementia, Parkinson's disease or brain tumor

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 35 and 85 years old?

Source: NCT05238272, who can take part

Where in Taiwan

  • Chang Gung Memotial HospitalTaoyuan, TaiwanContact: Ching-Yi Wu, ScDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Chang Gung Memorial Hospital
Trial code
NCT05238272
Record updated
14 February 2022
Original description
The primary aim of this project will be to determine the effects of the tRNS-augmented unilateral and bilateral MT, and their effects relative to the control interventions (sham tRNS with unilateral or bilateral MT) on restoring health outcomes including motor function, daily function, quality of life and self-efficacy, and motor control strategy as well as brain activities (electroencephalography, EEG) in stroke patients.Read full original descriptionShow less

Novel Brain Neurotechnology for Optimizing Precision Mirror Therapy in Stroke

The primary aim of this project will be to determine the effects of the tRNS-augmented unilateral and bilateral MT, and their effects relative to the control interventions (sham tRNS with unilateral or bilateral MT) on restoring health outcomes including motor function, daily function, quality of life and self-efficacy, and motor control strategy as well as brain activities (electroencephalography, EEG) in stroke patients.

Inclusion: ≥ 3 months onset from a first-ever unilateral stroke; an initial FMA scores between 18 to 56, indicating moderate to mild upper extremity motor impairment (Thielman, Kaminski, \& Gentile, 2008); age between 35 to 85; no excessive spasticity in any of the joints of the affected arm (shoulder, elbow, wrist and fingers); ability to follow instructions and perform tasks (Mini Mental State Examination scores ≥24); no participation in any neurorehabilitation experiments or drug clinical trials and; willing to provide written informed consent.

Exclusion: concomitant neurological conditions such as dementia, Parkinson's disease, brain tumor, brain injury and other brain diseases (such as intracranial hypertension or cerebral edema); Botulinum toxin injections 3 months before enrollment; have unstable cardiovascular status such as uncontrolled hypertension or New York Heart Association (NYHA) Class III/IV heart failure or are not suitable for receiving tRNS by the physician's assessments; contradiction to tRNS including a history of epilepsy, pregnant, having pacemakers and metallic implants in the neck and heads (Rossi, Hallett, Rossini, Pascual-Leone, \& Safety of, 2009); History of drug or alcohol abuse(Rossi et al., 2009).

ClinicalTrials.gov NCT05238272