Studies a heart hole closure in older people after unexplained stroke
Observes older adults with unexplained stroke and patent foramen ovale, a heart opening, and closure.
Plain-language title generated from the registry record
Registry title: Prospective Registry of Elderly ESUS With PFO
Key facts
- Where
- Seoul, South KoreaSee the site
Where in South Korea
- Asan Medical CenterSeoul, South KoreaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Asan Medical Center
- Trial code
- NCT05238610
- Record updated
- 14 February 2022
- Original description
Patent foramen ovale (PFO) is associated with an increased risk of stroke. PFO-closure was effective in preventing stroke in young stroke patients less than age 60 presented as an embolic stroke of undetermined source (ESUS). However, the benefit of PFO-closure in elderly ESUS patients is not clear. The investigators designed this prospective register-based observational study to verify the efficacy of PFO-closure in elderly ESUS patients with high-risk PFO, older than 60 yearsRead full original descriptionShow less
Prospective Registry of Elderly Patients With ESUS to Evaluate the Role of Covert Atrial Fibrillation and Patent Foramen Ovale
Patent foramen ovale (PFO) is associated with an increased risk of stroke. PFO-closure was effective in preventing stroke in young stroke patients less than age 60 presented as an embolic stroke of undetermined source (ESUS). However, the benefit of PFO-closure in elderly ESUS patients is not clear. The investigators designed this prospective register-based observational study to verify the efficacy of PFO-closure in elderly ESUS patients with high-risk PFO, older than 60 years
Inclusion: Patients older than 60 years-old; Patients diagnosed as ESUS within 180 days from onset; PFO found from TTE or TEE, which attributed to the ischemic stroke; Patients or their legal representative agreed to participate.
Exclusion: Patients with ischemic stroke at the vascular territory with significant stenosis; Patients with high risk cardioembolic stroke detected from EKG, Holter monitoring or echocardiography; Patients with other causes which may cause stroke (i.e. vasculitis, dissection, vasospasm, drug related or Moyamoya disease); Patients with active cancer; Patients with active internal bleeding; Patients with transient ischemic attack; Patients who need long term anticoagulation; Patients who have side effect on antiplatelet treatment; Patients who refuse to participate.