TerminatedNo phase
The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease
Key facts
- Who runs it
- Icahn School of Medicine at Mount Sinai
- Where
- New York, United StatesSee the site
- Trial code
- Status
- Terminated
- People taking part
- 16 people enrolled
- Started
- 24 Jan 2022
- Ended
- 24 Oct 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Chair Yoga
- Record updated
- 11 February 2026
- Why it stopped
- We have closed the study as subjects were not interested in participating.
Who can take part
- Age
- 18 years to 80 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Subjects eligible for the study are 18-80 year old adults
- Underwent percutaneous coronary intervention (PCI) at the catheterization lab of Mount Sinai Hospital (New York, New York) or have non-obstructive coronary artery disease and at least one CVD risk factor (hypertension, hypercholesterolemia, diabetes mellitus, or obesity) or metabolic abnormality (fasting plasma glucose ≥ 100 mg/dl, documented previous diagnosis of hypertension, serum triglycerides ≥ 150 mg/dl, or HDL cholesterol < 40 mg/dl)
- Subjects diagnosed with metabolic syndrome, which is defined as three or more of the following conditions: (1) Central or abdominal obesity (waist circumference > 40 inches for men and > 35 inches for women); (2) High triglycerides (≥150 mg/dL or triglycerides treatment); (3) Low HDL cholesterol (<40 mg/dL for men and <50 mg/dL for women) or low HDL-C treatment; (4) High blood pressure (≥130/85 mmHg) or antihypertensive medications; (5) High fasting glucose (≥100 mg/dL) or type 2 diabetes mellitus
- Participants must be able to willingly consent to study participation and must be able to comply with the study requirements
Who cannot take part
- Congestive heart failure, known arrthymias or prior Automated Implantable Cardioverter-Defibrillator /pacemaker or any metallic implants,
- Rheumatological/immunological diseases,
- History of transplant,
- Moderate to severe chronic obstructive pulmonary disease, debilitating or severe systemic Illness,
- Liver disease or alcohol use of more than 7 alcoholic drinks/week in women and more than 14 drinks/week in men
- Physical/psychological limitation or unwillingness to practice yoga,
- Subjects who are pregnant or postpartum less than 6 months,
Where in United States
- Mount Sinai HospitalNew York, United StatesNo longer taking part
About the trial
What the trial wants to find out
The aim of the prospective randomized single center study is to evaluate the effect of a short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease (CVD) risk factors in patients with CVD.
The 2 groups in the trial
- YogaExisting treatment, for comparison
Patients randomized to Yoga arm will practice chair yoga for 30 minutes at least three days a week for 16 weeks
Treatment: Chair Yoga
- Standard of CareNo study treatment, for comparison
Control group patients will follow standard of care (SOC) treatment.
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 11 February 2026