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TerminatedNo phase

The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease

Key facts

Who runs it
Icahn School of Medicine at Mount Sinai
Where
New York, United StatesSee the site
Trial code
Status
Terminated
People taking part
16 people enrolled
Started
24 Jan 2022
Ended
24 Oct 2025
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Chair Yoga
Record updated
11 February 2026
Why it stopped
We have closed the study as subjects were not interested in participating.

Who can take part

Age
18 years to 80 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Subjects eligible for the study are 18-80 year old adults
  • Underwent percutaneous coronary intervention (PCI) at the catheterization lab of Mount Sinai Hospital (New York, New York) or have non-obstructive coronary artery disease and at least one CVD risk factor (hypertension, hypercholesterolemia, diabetes mellitus, or obesity) or metabolic abnormality (fasting plasma glucose ≥ 100 mg/dl, documented previous diagnosis of hypertension, serum triglycerides ≥ 150 mg/dl, or HDL cholesterol < 40 mg/dl)
  • Subjects diagnosed with metabolic syndrome, which is defined as three or more of the following conditions: (1) Central or abdominal obesity (waist circumference > 40 inches for men and > 35 inches for women); (2) High triglycerides (≥150 mg/dL or triglycerides treatment); (3) Low HDL cholesterol (<40 mg/dL for men and <50 mg/dL for women) or low HDL-C treatment; (4) High blood pressure (≥130/85 mmHg) or antihypertensive medications; (5) High fasting glucose (≥100 mg/dL) or type 2 diabetes mellitus
  • Participants must be able to willingly consent to study participation and must be able to comply with the study requirements

Who cannot take part

  • Congestive heart failure, known arrthymias or prior Automated Implantable Cardioverter-Defibrillator /pacemaker or any metallic implants,
  • Rheumatological/immunological diseases,
  • History of transplant,
  • Moderate to severe chronic obstructive pulmonary disease, debilitating or severe systemic Illness,
  • Liver disease or alcohol use of more than 7 alcoholic drinks/week in women and more than 14 drinks/week in men
  • Physical/psychological limitation or unwillingness to practice yoga,
  • Subjects who are pregnant or postpartum less than 6 months,

Where in United States

  • Mount Sinai HospitalNew York, United StatesNo longer taking part

About the trial

What the trial wants to find out

The aim of the prospective randomized single center study is to evaluate the effect of a short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease (CVD) risk factors in patients with CVD.

The 2 groups in the trial

  • YogaExisting treatment, for comparison

    Patients randomized to Yoga arm will practice chair yoga for 30 minutes at least three days a week for 16 weeks

    Treatment: Chair Yoga

  • Standard of CareNo study treatment, for comparison

    Control group patients will follow standard of care (SOC) treatment.

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
11 February 2026