Studies how supervised exercise affects heart failure patients' bodies
Tests supervised exercise in people with heart failure, examining heart, lungs and muscles.
Plain-language title generated from the registry record
Registry title: Exercise Intervention in Patients With Heart Failure With Preserved and Reduced Ejection Fraction
Key facts
- Where
- Lund, SwedenSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 90 years old?
Source: NCT05255172, who can take part
Where in Sweden
- Skåne University Hospital LundLund, SwedenNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Region Skane
- Trial code
- NCT05255172
- Record updated
- 29 June 2025
- Original description
The objective of this study is to assess by what physiological mechanisms patients with heart failure benefit from exercise. Effects of an exercise intervention will be assessed for both central (heart and lungs) and peripheral (muscle fiber and mitochondria) factors.Read full original descriptionShow less
Physiological Mechanisms Affecting Exercise Capacity in Patients With Heart Failure - an Exercise Intervention Study Evaluated With Several Modalities
The objective of this study is to assess by what physiological mechanisms patients with heart failure benefit from exercise. Effects of an exercise intervention will be assessed for both central (heart and lungs) and peripheral (muscle fiber and mitochondria) factors.
Inclusion: Signs and symptoms of heart failure; Age ≥50 years; Stable chronic heart failure (no hospitalizations within past month, no new medications past month); Able to understand and follow exercise prescription; Currently physically inactive (less than 150 minutes/week moderate intensity exercise).
Exclusion: Devices or implants not compatible with magnetic resonance imaging or exercise testing; Currently or within the past 6 months been involved in cardiac rehab with exercise; Any orthopedic or medical condition affecting participation in testing and training; Moderate or severe valvular disease; Moderate or severe chronic obstructive pulmonary disease; Signs of acute ischemia during baseline cardiopulmonary exercise testing; Participation in other clinical trials that may affect results; Atrial fibrillation; NYHA class IV.