Pathophysiological Endotyping Using Baseline Polysomnography Data
Key facts
- Who runs it
- University Hospital, Antwerp
- Where
- Edegem, BelgiumSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 1,000 people, planned
- Started
- 1 Feb 2022
- Planned end
- Jan 2026
- Type of study
- Observational
- Treatments tested
- Drug-induced sleep endoscopy
- Record updated
- 13 February 2025
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- 18 years or older
- Diagnosis with OSA (AHI ≥ 5)
- Eligible for drug-induced sleep endoscopy as the next step in the clinical path for OSA
- Capable of giving informed consent
Who cannot take part
- Medication use related to sleeping disorders
- Central Sleep Apnea Syndrome
- Medical history of known causes of tiredness by day or severe sleep disruption (insomnia, PLMS, Narcolepsy)
- Seizure disorders
- Known medical history of intellectual disability, memory disorders or current psychiatric disorders (psychotic illness, major depression, or acute anxiety attacks as mentioned by the patient)
- Diagnostic polysomnography data not available at the Antwerp University Hospital
- Factors indicative of unstable clinical status or would preclude DISE investigation:
- Pregnancy or willing to become pregnant
Where in Belgium
- Antwerp University HospitalEdegem, BelgiumContact: Olivier M Vanderveken, MD, PhDTaking people
About the trial
What the trial wants to find out
The study is designed to develop models to predict site of collapse information using routine polysomnography. In an observational study, the investigators will study 1000 patients with obstructive sleep apnea (OSA) who have had a recent polysomnographic study and will undergo drug-induced sleep endoscopy (DISE) as part of their standard clinical care. Flow shape information from the polysomnographic study will be associated with the DISE results, and a set of prediction models will be developed and validated to detect the site, pattern and degree of upper airway collapse as seen during DISE.
The group in the trial
- Obstructive sleep apnea patients eligible for DISE
Patients with obstructive sleep apnea (AHI\>=5) will be included in the study. Subjects should be eligible for drug-induced sleep endoscopy as the next step in their clinical path.
Treatment: Drug-induced sleep endoscopy
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Prediction of Drug-Induced Sleep Endoscopy Outcome From Baseline Diagnostic Data Including Polysomnography
- Record updated
- 13 February 2025