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Taking people in South KoreaNo phase

Checks tiny heart blood vessels in heart attacks with clear arteries

Compares heart outcomes by testing small heart vessels in adults with MINOCA.

Plain-language title generated from the registry record
Registry title: Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Key facts

Where
Gwangju, South KoreaSee the site

Where in South Korea

  • Chonnam National University HospitalGwangju, South KoreaTaking people

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Trial details

Who runs it
Chonnam National University Hospital
Trial code
NCT05272618
Record updated
12 May 2026
Original description
To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomography (OCT), invasive and non-invasive coronary physiologic assessment.Read full original descriptionShow less

Clinical Relevance of Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomography (OCT), invasive and non-invasive coronary physiologic assessment.

Inclusion: Subject with age ≥19 years and acute myocardial infarction; Rise and/or fall of cardiac troponin with one level >99 percentile plus ischemic signs/symptoms; Subject with non-obstructive coronary arteries; <50% diameter stenosis or; fractional flow reserve (FFR) >0.80 ③ Subject without previous history of coronary artery disease; Subject who performed invasive coronary angiography within 24 hours after presentation ⑤ Subject who eligible for invasive and non-invasive coronary physiologic assessment.

Exclusion: Subject with obstructive coronary arteries; Subject with alternate diagnosis including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies; Subject with cardiogenic shock or cardiac arrest ④ Subject who has non-cardiac co-morbid conditions with life expectancy <1 year ⑤ Subject or lactating women ⑥ Subject unable to provide consent.

ClinicalTrials.gov NCT05272618