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Muscle Vibration Study for Brain Injury Recovery in Adults

Studies brain changes during muscle vibration therapy in adults with stroke or brain injury.

Plain-language title generated from the registry record
Registry title: Neuroplasticity After Proprioceptive Rehabiliation

Key facts

Where
Paris, FranceSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 70 years old?

Source: NCT05277519, who can take part

Where in France

  • Pitié Salpêtrière HospitalParis, FranceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Institut National de la Santé Et de la Recherche Médicale, France
Trial code
NCT05277519
Record updated
7 July 2026
Original description
Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the neuroplastic changes during and after instrumented proprioceptive rehabilitation relying on sequences of muscle vibration in subacute stroke stages.Read full original descriptionShow less

Neuroplasticity Induced by Functional Muscle Tendon Vibrations in Patients With Acquired Brain Injury

Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the neuroplastic changes during and after instrumented proprioceptive rehabilitation relying on sequences of muscle vibration in subacute stroke stages.

Inclusion: hemiparesis at least transient in lower limb following an acquired brain injury (stroke or traumatic brain injury); French spoken; Affiliated to a French social insurance; No previous traumatic, vascular or neurodegenerative injuries; Having presented during the acute phase or presenting a motor deficit of one of the lower limbs; Presenting an absence of autonomy of walking at the entrance of the rehabilitation department; In the sub-acute phase, i.e. from 15 days to 6 months after the accident; Presenting moderate cognitive disorders allowing them to understand instructions and give their consent.

Exclusion: strong cognitive disorders; maintenance of justice, tutelage, legal guardianship; Pregnancy and breastfeeding; Outpatients who do not have weekly follow-up in the rehabilitation department.

ClinicalTrials.gov NCT05277519