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Brain Training Using Near-infrared Spectroscopy for Food Craving in Obesity

Tests brain-activity neurofeedback training to reduce food craving in adults with obesity.

Plain-language title generated from the registry record
Registry title: Neurofeedback Based on Near-infrared Spectroscopy as a Therapy for Food Addiction in Obese Subjects.

Key facts

Where
Rennes, FranceSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 55 years old?

Source: NCT05277714, who can take part

Where in France

  • CHU RennesRennes, FranceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Rennes University Hospital
Trial code
NCT05277714
Record updated
8 August 2025
Original description
The hypothesis is that the increase in dlPFC brain activity via near-infrared spectroscopy-based Neurofeedback (fNIRS-based NF) training based on near-infrared spectroscopy would allow an improvement of the eating behavior, thus promoting a long-term weight loss in obese subjects.Read full original descriptionShow less

Neurofeedback Based on Near-infrared Spectroscopy as a Therapy for Food Addiction in Obese Subjects.

The hypothesis is that the increase in dlPFC brain activity via near-infrared spectroscopy-based Neurofeedback (fNIRS-based NF) training based on near-infrared spectroscopy would allow an improvement of the eating behavior, thus promoting a long-term weight loss in obese subjects.

Patients will be trained during a month with 8 NF sessions and results based on clinical data and different questionnaires results will be compared between inclusion and 3 months later

Inclusion: Eligible for obesity surgery according to the 2009 French High Authority on Health (HAS) criteria (BMI ≥40 or BMI ≥35 with comorbidities); Right-handed; Presenting a food addiction determined by the YFAS 2.0 questionnaire ; Affiliated to a social security system; Having given free and informed consent in writing.

Exclusion: Psychotropic drugs, except antidepressants stabilized for at least 3 weeks and benzodiazepines; Psychotic psychiatric disorders (schizophrenic disorders and bipolar disorders); History of bariatric surgery; Persons of legal age under legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty; Addiction to alcohol or other psychoactive substances (except tobacco); Current treatment in the nutrition unit; Insufficient command of French; Pregnant or breast-feeding woman; Contraindications to fMRI; Inability to perform the fNIRS procedure due to blockage or attenuation of the light at the capillary level.

ClinicalTrials.gov NCT05277714