Studies cell changes in hip osteoarthritis in people having hip replacement surgery
Studies cells in hip joints of adults with hip osteoarthritis undergoing hip replacement surgery.
Plain-language title generated from the registry record
Registry title: Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis
Key facts
- Where
- Espoo and Turku, FinlandSee the 4 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 74 years old?
Source: NCT05278520, who can take part
Where in Finland
- Helsinki University HospitalEspoo, FinlandTaking people
- Turku University HospitalTurku, FinlandTaking people
- PET-centre, University of TurkuTurku, FinlandNo longer taking part
- Turku Bioscience, University of TurkuTurku, FinlandNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Turku
- Trial code
- NCT05278520
- Record updated
- 24 August 2025
- Original description
The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial omics.Read full original descriptionShow less
Studies on the Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis
The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial omics.
Inclusion: Cases: Adult patients with osteoarthritis in the hip joint and who are going through an elective total hip arthroplasty; Controls: Non-arthritis adult patients who are going through a trauma-based emergency total hip arthroplasty; ----; Adult patients with rheumatoid arthritis in the hip joint and who are going through an elective total hip arthroplasty; ----.
Exclusion: The OA patients may not have diabetes, rheumatoid arthritis (RA), or metabolic syndrome; For the Rheumatoid sub-study, the exclusion criteria are the same as above except for the RA; Age < 18 or > 74; The body mass index must be below 35.