Robotic partial knee replacement compared with total knee replacement for knee osteoarthritis

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with end stage arthritis on the inner side of the knee who are on the list for knee replacement. It compares a standard total knee replacement with a robot-assisted partial knee replacement.

Age

50 to 75 years at the time of listing for surgery

Sex

Male or female

Disease stage

End stage osteoarthritis of the inner (medial) part of the knee. The anterior cruciate ligament and inner side ligament must be intact. The cartilage on the outer side must be full thickness and of good quality. The bow-leg (varus) shape must be correctable. ASA grade 1 or 2 (general health score before anaesthesia). People must be able to have both a cruciate retaining TKA (Triathlon prosthesis) and a UKA.

Earlier treatment

No prior knee surgery other than arthroscopy (keyhole surgery).

Main reasons for not taking part

• Bow-leg deformity of more than 20 degrees, or a knee that cannot straighten by more than 10 degrees
• Significant arthritis on the outer side of the knee, or the kneecap needs resurfacing
• Inflammatory disease such as rheumatoid arthritis, or past joint infection of the knee
• Foot, hip or spine problems that cause symptoms
• Pregnant, breastfeeding or planning pregnancy, or unable to follow the study (including refusing a CT scan)

The registry criteria, word for word

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

• Are you between 50 and 75 years old?YesNo

What the trial wants to find out

The purpose of this research is to compare the functional outcomes of patients with end stage medial compartment OA of the knee undergoing a conventional mTKA to those undergoing rUKA and to assess the associated cost economics of such technology.

The 2 groups in the trial

• Manual Total Knee ArthroplastyExisting treatment, for comparison

  This group will receive a conventional manual Triathlon (Stryker) TKA with a cruciate retaining polyethylene insert. The surgeon will then make bone cuts using a manual jig and a hand held saw to prepare the bone surfaces for the implant. A measured resection technique will be employed with a three degree tibial slope. The surgeon will use a conventional jig alignment technique for intramedullary referencing for the femur and extra medullary referencing for the tibia. Once the implant is in position the knee is then balanced by the "feel" though a range of movement and soft tissue releases will be performed as required to balance the knee in flexion and extension.

  Treatment: Triathlon (Stryker) Total Knee Arthroplasty

• Robotic Assisted Unicompartmental Knee ArthroplastyTreatment being tested

  This group will receive the cemented Restoris MCK (Mako, Stryker) with a highly crossed linked (X3) polyethylene insert through a less invasive to the knee joint. Instead of using a manual jig and a hand held burr will be used to prepare the bone surfaces for the implant, the MAKO robotic arm will be used by the surgeon to cut the bone at the required alignment. The information from the CT scan will be used to create a 3D model of the patient's bony anatomy and will used to plan the positioning of the implant. Once the trackers are in place registration of the knee joint surface is performed. The specified bone cuts are then performed using the robotic arm, aiming to gap balance the knee through a full range of movement.

  Treatment: MAKO™ Partial Knee Arthroplasty