Repetitive Transcranial Magnetic Stimulation to People With Cannabis Use Disorder (SToP-C-rTMS x CUD)
Key facts
- Who runs it
- The University of Hong Kong
- Where
- Hong Kong1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 20 people enrolled
- Started
- 1 Sept 2022
- Ended
- 31 Mar 2025
- Type of study
- Interventional, 3 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Repetitive Transcranial Magnetic Stimulation
- Record updated
- 8 July 2025
Who can take part
- Age
- 18 years to 65 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Able to read and communicate in English and/or Chinese SToP-C-rTMS x CUD
- Able to give informed consent
- Using cannabis or marijuana as the primary psychoactive substance of abuse
- Diagnosed with Cannabis Use Disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) by the Structured Clinical Interview for DSM-5 Disorders (SCID-5)
Who cannot take part
- Contra-indicated to have rTMS, including subjects with electronic and/or magnetic implants (e.g. pacemaker, implantable cardioverter defibrillator [ICD], cerebral shunts, cochlear implant, etc.), with metallic or mechanic fragments (e.g., screws, plates, stents, clips, etc.), pregnant, with any known or history of neurological conditions including cerebral vascular accidents, epilepsy, brain tumor or space occupying lesion, poorly controlled or unstable diabetes mellitus, and receiving unstable dose(s) of antipsychotics, antidepressants, benzodiazepines and/or anticonvulsants in the past 6 months
- Had been diagnosed with the following disorders, including neurodevelopmental disorders, DSM-5 defined substance use disorder greater than moderate in severity, and neurocognitive disorders
- Age <18 years old
- Unable to read English or Chinese
- Unable to give informed consent
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
This study is to explore if repetitive transcrinal magnetic stimulation (rTMS) with different stimulation schedules will be equally effective in reducing carving, frequency of cannabis use, and the severity of cannabis use disorder in participants suffering from cannabis use disorder (CUD).
Read full original descriptionShow less
The investigators assume the hypotheses as:
1. Multiple rTMS sessions can reduce craving for cannabis, severity of CUD, frequency and amount of cannabis use. 2. Different rTMS treatment schedules have differences in reducing the craving for cannabis and severity of CUD, and prolonging relapse of cannabis use.
The 3 groups in the trial
- Arm 1Existing treatment, for comparison
Subjects receive 20 rTMS sessions in 2 weeks
Treatment: Repetitive Transcranial Magnetic Stimulation
- Arm 2Existing treatment, for comparison
Subjects receive 20 rTMS sessions in 4 weeks
Treatment: Repetitive Transcranial Magnetic Stimulation
- Arm 3Existing treatment, for comparison
Subjects receive 20 rTMS sessions in 5 weeks
Treatment: Repetitive Transcranial Magnetic Stimulation
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Substance Misuse To Psychiatric Disorders-Repetitive Transcranial Magnetic Stimulation to People With Cannabis Use Disorder
- Publications
- Record updated
- 8 July 2025