Reducing Pain and Opioid Use With CBD

Who can take part

• Self-reported desire or intent to use cannabidiol to reduce pain and/or opioid use
• Must be 18 years of age or older

Who cannot take part

• Self-reported recreational drug use (other than opioids) in the past 30 days or failed urine screen for cocaine, benzodiazepines (if not prescribed), MDMA, sedatives, or methamphetamine
• Currently using CBD for medical reasons
• Self-reported current moderate/severe alcohol use, or severe opioid use disorder on the DSM V (unless patient is medically stable and approved by personal physician as well as the Medical Director for the study)
• Actively seeking or in treatment for or history of any substance use disorder, other than opioid use disorder
• Currently being treated for or diagnosed with a moderate, severe, or unstable medical illness (e.g., renal disease, liver disease, cardiovascular disease). If the person has had a recent operation, they must be cleared for study participation by their surgeon or primary care doctor. Study inclusion/exclusion will be evaluated by our medical director when there are questions about applying criteria
• Report being treated for bipolar disorder, schizophrenia, dissociative disorders, eating disorders, or any other psychotic or organic mental disorder in the last year
• Currently taking any of the following medications:; Those known to have a major interaction with Epidiolex (buprenorphine, leflunomide, levomethadyl acetate, lomitapide, mipomersen, pexidartinib, propoxyphene, sodium oxybate, and/or teriflunomide); Acute treatment with any antiepileptic medications (e.g. clobazam, sodium valproate)
• Females of childbearing potential who are pregnant, nursing, or who are not using a reliable form of birth control
• Endorsing item 2 on the C-SSRS measure of suicide risk