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The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients

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Trial details

Who runs it
Northern Jiangsu People's Hospital
Trial code
NCT05325424
Record updated
30 May 2025
Original description
In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.Read full original descriptionShow less

In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.

Inclusion: A clinical, radiological or histologic diagnosis of cirrhosis of any etiology; Splenomegaly with secondary hypersplenism, Platelet count < 50*10\^9/L; Informed consent to participate in the study.

Exclusion: Hepatocellular carcinoma or any other malignancy,; Recent peptic ulcer disease; History of Hemorrhagic stroke; Uncontrolled Hypertension; Bleeding portal hypertension; Human immunodeficiency virus (HIV) infection; Child-Pugh grade C; Pregnancy.

ClinicalTrials.gov NCT05325424