Tests surgery to remove the spleen and disconnect veins in cirrhosis
Tests spleen removal with vein disconnection in adults with liver cirrhosis.
Plain-language title generated from the registry record
Registry title: The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients
Key facts
- Where
- Yangzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with liver cirrhosis, an enlarged spleen and bleeding from veins in the gullet or stomach. It studies surgery on the spleen and nearby veins.
- Age
- 18 years or older
- Sex
- Men and women can join.
- Disease stage
- Cirrhosis of any cause, with an enlarged spleen and secondary hypersplenism, and bleeding from varicose veins in the gullet or stomach. Child-Pugh grade C cannot join.
Main reasons for not taking part
- Liver cancer or any other cancer
- Child-Pugh grade C
- Recent stomach ulcer disease
- History of bleeding stroke
- Pregnancy, uncontrolled high blood pressure, or HIV infection
Read by machine on 12 November 2026.
Where in China
- Clinical Medical College of Yangzhou UniversityYangzhou, ChinaContact: Guo-Qing Jiang, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Northern Jiangsu People's Hospital
- Trial code
- NCT05325437
- Record updated
- 30 May 2025
- Original description
In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.Read full original descriptionShow less
The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients
In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.
Inclusion: A clinical, radiological or histologic diagnosis of cirrhosis of any etiology; Splenomegaly with secondary hypersplenism; gastroesophageal variceal bleeding; Informed consent to participate in the study.
Exclusion: Hepatocellular carcinoma or any other malignancy,; Recent peptic ulcer disease; History of Hemorrhagic stroke; Uncontrolled Hypertension; Human immunodeficiency virus (HIV) infection; Child-Pugh grade C; Pregnancy.