Kidney Biopsies to Study Kidney Problems After Liver Transplant
Studies kidney biopsies in adults with liver transplants and reduced kidney function.
Plain-language title generated from the registry record
Registry title: Renal Biopsies in Post-liver Transplantation Patients With Renal Impairment
Key facts
- Where
- Shanghai, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05326399, who can take part
Where in China
- Ren Ji Hospital, Shanghai Jiao Tong University School of MedicineShanghai, ChinaNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- RenJi Hospital
- Trial code
- NCT05326399
- Record updated
- 28 November 2025
- Original description
Investigators will conduct this single-center, prospective cohort study to explore the prevalence and risk factors of renal function progression in post-liver transplantation patients with renal impairment after renal biospy and to understand the the pathology of kidney disease in post-liver transplantation patients with renal impairment.Read full original descriptionShow less
Renal Biopsies in Post-liver Transplantation Patients With Renal Impairment: a Single-center, Prospective Cohort Study
Investigators will conduct this single-center, prospective cohort study to explore the prevalence and risk factors of renal function progression in post-liver transplantation patients with renal impairment after renal biospy and to understand the the pathology of kidney disease in post-liver transplantation patients with renal impairment.
Inclusion: age 18-75 years; patients received liver transplantation; new onset of proteinuria(defined as 24-hour proteinuria>1g/24h, or Urinary albumin creatinine ratio(UACR)>300mg/g on at least two occasions), and/or renal impairment: eGFR <60 mL/min/1.73 m² at least two occasions, and/or serum creatinine increase ≥50% from baseline; have received renal biopsy in the past 3 months; Signed informed consent form(ICF).
Exclusion: patients received renal transplantation; hepatic failure; uncontrolled mental disease or unable to cooperate during operation; severe bleeding risk or platelet <70*109/L; chronic kidney insufficiency with eGFR<30ml/min·1.73m2,or kidney atrophy, or solitary kidney, or medullary sponge kidney, or polycystic kidney, or obstructive nephropathy; Pregnancy or lactation; not suitable for this study judged by investigaters.