Implanted heart monitor to find atrial fibrillation after heart attack without blocked arteries
Tests a small implanted heart monitor in adults with a heart attack without blocked arteries.
Plain-language title generated from the registry record
Registry title: Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA
Key facts
- Where
- Bern and Zurich, SwitzerlandSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT05326828, who can take part
Where in Switzerland
- Bern University Hospital, InselspitalBern, SwitzerlandTaking people
- University Hospital Zurich (USZ)Zurich, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Insel Gruppe AG, University Hospital Bern
- Trial code
- NCT05326828
- Record updated
- 30 October 2024
- Original description
Myocardial infarction with non-obstructive coronary arteries (MINOCA) (i.e.<50% stenoses) on coronary angiography) is an underappreciated clinical entity concerning 5-6% of patients with acute myocardial infarction. Approximately 50% of these patients remain without appropriate diagnosis and treatment.Read full original descriptionShow less
Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA
Myocardial infarction with non-obstructive coronary arteries (MINOCA) (i.e.<50% stenoses) on coronary angiography) is an underappreciated clinical entity concerning 5-6% of patients with acute myocardial infarction. Approximately 50% of these patients remain without appropriate diagnosis and treatment.
The MINOCA study aims at systematically assessing the frequency of underlying pathologies of MINOCA and outcomes with a multidisciplinary etiologic work-up and follow-up of 5 years including, for the first time, an implantable cardiac monitor (ICM) to assess the frequency of atrial fibrillation as underlying cause for MINOCA.
Inclusion: ≥18 years of age; Written informed consent; Acute myocardial infarction (AMI) type 1 in accordance with the 4th universal definition of myocardial infarction; Non-obstructive coronary arteries on angiography defined as the absence of coronary artery stenoses ≥50% in any potential infarct-related artery; No clinically overt specific cause for the acute presentation; Subendocardial or transmural late gadolinum enhancement (LGE) consistent with an ischemic etiology on cardiac magnetic resonance imaging (CMR); No clear underlying cause of MINOCA and therefore increased probability of atrial fibrillation; ≥18 years of age; Written informed consent; AMI type 1 in accordance with the 4th universal definition of myocardial infarction; Non-obstructive coronary arteries on angiography defined as the absence of coronary artery stenoses ≥50% in any potential infarct-related artery; No clinically overt specific cause for the acute presentation; Subendocardial or transmural LGE consistent with an ischemic etiology on CMR.
Exclusion: Previous MI; Previous percutaneous coronary intervention (PCI); Previous coronary artery bypass grafting (CABG); Previous MI; Previous PCI; Previous CABG; History of atrial fibrillation or atrial flutter ablation; Known coronary artery disease; Known coronary artery disease; Contraindications to CMR (i.e. non-MR-compatible implantable cardiac device, glomerular filtration rate (GFR) <30 ml/min); Contraindications to CMR (i.e. non-MR-compatible implantable cardiac device, GFR <30 ml/min); Known atrial fibrillation or atrial flutter; Contraindications to ICM implantation; Clear underlying cause of MINOCA before ICM implantation.