NCT05333978Terminated
Optoacoustic Detection of Inflammation Using MSOT Device
Optoacoustic Detection of Inflammation Using Multispectral Optoacoustic Tomography
Source: ClinicalTrials.gov · Last updated 1 Jun 2026
Reason given: Administrative Reasons
Brief summary (registry, in English)
The purpose of this study is to evaluate the safety and potential of a new experimental imaging instrument called multispectral optoacoustic tomography (MSOT) to detect inflammation in patients with chronic graft versus host disease of the skin or GI tract, Crohn's disease, or Colitis disease.
- Status (registry)
- Terminated
- Study type
- Interventional
- Enrollment
- 29 (actual)
- First submitted
- 21 Feb 2022
- Start date
- 31 May 2022
- Primary completion date
- 20 Apr 2026
- Lead sponsor
- University of Oklahoma
- Diseases
- Crohn's disease
- NCT number
- NCT05333978
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any open wound (skin ulcerations or infections) at or near the site of imaging that would preclude MSOT imaging.
- Any febrile illness that precludes or delays participation preoperatively
Other
- Patients with a tattoo over the area of inflammation
- Pregnant patients are not eligible for this trial. Eligible patients (if applicable) will be required to document the date of the first day of their last menstrual cycle, and provide a negative pregnancy test if sexually active and of childbearing potential
- Patients who are breastfeeding
Who the study is looking for
- Patients documented clinical/pathologic 1) acute or chronic colon or skin GVHD, 2) Crohn's disease, or 3) colitis
- Have acceptable hematologic status [total hemoglobin (tHb) ≥ 7.0 mg/dL]
- Patients ≥ 18 yrs of age
- Willing to comply with study procedures and be available for the duration of the study
- Patient has ability to understand and the willingness to provide a signed and dated IRB-approved informed consent document.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Oklahoma Health Sciences Center, Stephenson Cancer Center | Oklahoma City | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.