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The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis Patients

Key facts

Where
Yangzhou, ChinaSee the site

Where in China

  • Clinical Medical College, Yangzhou UniversityYangzhou, ChinaContact: Guo-Qing Jiang, MDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
Northern Jiangsu People's Hospital
Trial code
NCT05338294
Record updated
28 May 2025
Original description
In this study, the investigators compared the improvement of immune function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative immune function and improve patient prognosis.Read full original descriptionShow less

In this study, the investigators compared the improvement of immune function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative immune function and improve patient prognosis.

Inclusion: A clinical, radiological or histologic diagnosis of cirrhosis of any etiology; Splenomegaly with secondary hypersplenism; gastroesophageal variceal bleeding; Informed consent to participate in the study.

Exclusion: Hepatocellular carcinoma or any other malignancy,; Recent peptic ulcer disease; History of Hemorrhagic stroke; Uncontrolled Hypertension; Human immunodeficiency virus (HIV) infection; Child-Pugh grade C; Pregnancy.

ClinicalTrials.gov NCT05338294