How sleep, diet and activity before pregnancy relate to female infertility
Looks at how lifestyle before conception relates to later reproductive outcomes in women.
Key facts
- Who runs it
- Northwestern University
- Where
- Chicago, United StatesSee the site
- Trial code
- Registry title
- PROspective Study of Mothers' and Infants' Social and Epidemiologic Determinants of Health
- Status
- Recruiting
- People taking part
- 1,000 people, planned
- Started
- 7 Sept 2021
- Expected to end
- Dec 2046
- Type of study
- Observational
- Record updated
- 16 June 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 18 to 44 trying to get pregnant at Northwestern Fertility and Reproductive Medicine (FRM). It studies how lifestyle before pregnancy, such as sleep, food and exercise, affects having a baby.
- Age
- 18 to 44 years
- Sex
- Women only
- Disease stage
- Women trying to get pregnant at a fertility clinic. Participants must agree to be followed for up to 25 years and to share information about their child's health.
- Earlier treatment
- No earlier IVF cycles.
Main reasons for not taking part
- Women using donor eggs (donor oocytes)
- Women using a gestational carrier (another woman carrying the pregnancy)
- Not able or not willing to give informed consent for any part of the study
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Women ages 18-44 seeking pregnancy at Northwestern Fertility and Reproductive Medicine (FRM) who agree to; Be followed for a period for up to 25 years; Share information regarding their child's health
- No prior IVF cycles
Who cannot take part
- Women using donor oocytes or gestational carriers
- Inability or unwillingness to provide informed consent for any aspects of the study
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 44 years old?
Where in United States
- Northwestern Medicine Fertility and Reproductive MedicineChicago, United StatesContact: Emily Jungheim, MD, MSCITaking people
About the trial
What the trial wants to find out
The goal of the PROMISE study is to determine how pre-conception lifestyle factors (e.g., sleep, nutrition, physical activity) affect short- and long-term reproductive outcomes.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The PROMISE Study: PROspective Study of Mothers' and Infants' Social and Epidemiologic Determinants of Health
- Plain-language title
- How sleep, diet and activity before pregnancy relate to female infertilityGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 15 November 2026.
- Fit questions
- Built from NCT05358483, who can take part
- Record updated
- 16 June 2026