Retinal imaging with adaptive optics in people with glaucoma
Collects eye images using adaptive optics technology in adults with open-angle glaucoma.
Plain-language title generated from the registry record
Registry title: Adaptive Optics Retinal Imaging
Key facts
- Where
- Silver Spring, United StatesSee the site
Where in United States
- Food and Drug AdministrationSilver Spring, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Food and Drug Administration (FDA)
- Trial code
- NCT05370287
- Record updated
- 8 May 2026
- Original description
The objective of the study is to collect and assess adaptive optics (AO) retinal images from human subjects in support of projects to demonstrate, advance, and enhance clinical use of AO technology.Read full original descriptionShow less
Adaptive Optics Retinal Imaging
The objective of the study is to collect and assess adaptive optics (AO) retinal images from human subjects in support of projects to demonstrate, advance, and enhance clinical use of AO technology.
Inclusion: Are 21 years of age or older; Have the ability to cooperate with instructions during adaptive optics imaging (similar to instructions given during a clinical eye exam); Have the ability to understand and sign an informed consent; Have been diagnosed with POAG (cohort 2).
Exclusion: Have a condition which prevents adequate images from being obtained (e.g. unstable fixation or media opacity); Have a history of adverse reaction to mydriatic drops; Have a predisposition to (i.e., narrow iridocorneal angle) or any history of acute angle closure glaucoma (AACG); Have any health conditions that would contraindicate oxygen supplementation, including chronic obstructive pulmonary disease (COPD), emphysema, asthma, or any other obstructive or restrictive lung disease (RBF experiment participants only); Have tested positive for COVID-19 at initial enrollment or have acute or chronic photophobia as a result of contraction; Are under 21 years of age; Have visual correction outside of the range +4 diopters (D) to -8 D; Do not meet the criteria for POAG as defined by the American Academy of Ophthalmology Practice Patterns (cohort 2); Have a dependency on oxygen support or a baseline oxygen saturation <95% (RBF experiment participants only); Are working under the direct supervision of Dr. Hammer.