Compares surgical and imaging staging before chemoradiation for advanced cervical cancer
Tests lymph node surgery before chemoradiation in adults with locally advanced cervical cancer.
Plain-language title generated from the registry record
Registry title: Comparing the Efficacy of Surgery Staging and Image Staging of Locally Advanced Cervical Cancer
Key facts
- Where
- Chongqing, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 18 to 75 with locally advanced cervical cancer. It compares surgical staging with imaging staging.
- Age
- 18 to 75 years
- Sex
- Women only
- Disease stage
- Squamous cell carcinoma, adenocarcinoma or adenosquamous cell carcinoma of the cervix, FIGO 2018 stage IB3, IIA2, or IIB to IVA. ECOG score 0 to 1. Expected survival over 6 months.
- Earlier treatment
- No pelvic radiotherapy, no pelvic artery embolization, and no partial or radical hysterectomy before.
Main reasons for not taking part
- Positive para-aortic lymph nodes on CT, MRI or PET/CT
- Another cancer diagnosed within five years or needing treatment
- HIV positive or other immune deficiency
- Chronic kidney insufficiency or kidney failure, or liver cirrhosis
- Severe heart disease such as a heart attack or serious heart failure
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05378087, who can take part
Where in China
- Chongqing University Cancer HospitalChongqing, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Chongqing University Cancer Hospital
- Trial code
- NCT05378087
- Record updated
- 31 August 2023
- Original description
The study is a domestic multicenter, prospective, non-randomized controlled concurrent trial. It will be assessed whether surgery staging on locally advanced cervical cancer is superior to image staging for improving progression-free survival and overall survival.Read full original descriptionShow less
Non-randomized Concurrent Controlled Trial of Surgery Staging or Image Staging of Locally Advanced Cervical Cancer
The study is a domestic multicenter, prospective, non-randomized controlled concurrent trial. It will be assessed whether surgery staging on locally advanced cervical cancer is superior to image staging for improving progression-free survival and overall survival.
Inclusion: The patients with good compliance, voluntarily signed the informed consent form and participated in the study; Histopathology: squamous cell carcinoma, adenocarcinoma, adenosquamous cell carcinoma; Stage (FIGO2018): IB3, IIA2, IIB-IVA; ECOG score: 0 ~ 1; The expected survival >6 months; The result of a pregnancy test (serum or urine) within seven days must be negative for women of childbearing age, who must take contraception during the trial.
Exclusion: The drugs for the treatment of concomitant disease seriously impaired liver or kidney function, such as tuberculosis; Other concomitant diseases or special conditions seriously endanger the patient's health or interfere with the trial; Activity or uncontrol severe infection; Liver cirrhosis or other decompensated liver disease; A history of immune deficiency, including HIV positive or a congenital immunodeficiency disease; Chronic renal insufficiency or renal failure; Other malignancies were diagnosed within five years or needed treatments; Myocardial infarction, severe arrhythmia and congestive heart failure with grade ≥2 (New York heart association); A history of pelvic artery embolization; A history of pelvic radiotherapy; A history of partial hysterectomy or radical hysterectomy; A history of severe allergic reaction to platinum drugs; The CT/MRI/PET/CT show that the para-aortic lymph nodes are positive; Patients who cannot understand the research regimen and refuse to sign the informed consent form.