UNICORNS: Uveitis in Childhood Prospective National Cohort Study
Key facts
- Who runs it
- Institute of Child Health
- Where
- United Kingdom31 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Active, not recruiting
- People taking part
- 250 people, planned
- Started
- 22 Oct 2020
- Expected to end
- Dec 2026
- Type of study
- Observational
- Record updated
- 4 October 2024
Who can take part
- Age
- Up to 18 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Children newly diagnosed with uveitis (within previous 6 months)
- Age < 18years
Who cannot take part
- Uveitis due to ocular trauma (including iatrogenic, ie intraocular surgery)
- Uveitis due to malignancy
- Uveitis due to confirmed ocular infection
- Children with developmental disorders or impairments which prevent their self-report of their function level or quality of life
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Childhood uveitis (inflammation inside the eye) is an uncommon disorder that carries the risk of blindness. Inadequate treatment of active inflammation has been shown to be related to a poor outcome. There has been no population-based, prospective longitudinal study of all-cause childhood uveitis, with resultant limitations in the evidence base used to counsel affected families, balance treatment decisions, or plan further research. The aim of the study is to describe the characteristics of childhood-onset uveitis and describe outcomes. The investigators shall also aim to identify the socio-demographic, clinical, biological and treatment-related determinants of outcome. Early (1-2 years following diagnosis) outcomes will be described in the first instance: However, through the creation of a national inception cohort, the investigators shall enable longer-term studies of outcome for affected children and families. There will be no change to routine clinical care.
The group in the trial
- Childhood Uveitis
Children \<18 years old newly diagnosed with non-infectious uveitis
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Uveitis in Childhood Prospective National Cohort Study
- Record updated
- 4 October 2024