Fact CheckerSign in

NCT05420233Active, not recruiting

The CROCO Study: CROhn's Disease COhort Study

Source: ClinicalTrials.gov · Last updated 28 Jul 2026

Brief summary (registry, in English)

The investigators propose to create a prospective Crohn Disease cohort, where patients receiving the most up-to-date therapies with a treat-to-target strategy, will be closely followed to characterize the progression of Crohn Disease by measuring the Lémann Index over time. The goal of the CROCO Study - "Crohn's Disease Cohort Study" is to promote a greater understanding of the long-term evolution of Crohn Disease , to describe prospectively the impact of different therapeutic strategies and develop accurate predictors of bowel disease damage and disability.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
533 (actual)
First submitted
25 May 2022
Start date
1 Aug 2021
Primary completion date
Jul 2030
Lead sponsor
GLSMED Learning Health S.A.
NCT number
NCT05420233

What you commit to

  • Study type: Interventional
  • Participants enrolled: 533
  • From 1 Aug 2021 to the primary completion date, Jul 2030
  • 19 sites in 11 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Refusal or medical conditions (e.g. Glomerular filtration rate \< 30 mL/min) preventing cross-sectional imaging during follow-up;

Age

  • Severe underlying medical disorder with an anticipated life expectancy \< 2 years;

Other

  • Patients unwilling or unable to provide informed, written consent;
  • Uncertain CD diagnosis;
  • Pregnancy (if it is impossible to implement the MRE at one year) or any other reason that makes resonance not feasible throughout the study (eg claustrophobia).

Who the study is looking for

  • To be eligible all of the following criteria must be met:
  • Diagnosis of CD (according to ECCO guidelines) established within the past 12 months;
  • Patients able to understand the information provided to them and to give written informed consent for the study;
  • Male or female, age \> 18 years.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (19)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Hospital CHU of Liège
Coordinator of this site? Confirm its status
LiègeBelgiumUnknown status
American Gastroenterology Center
Coordinator of this site? Confirm its status
StróvolosCyprusUnknown status
IBD Clinical and Research Clinic, ISCARE
Coordinator of this site? Confirm its status
PragueCzechiaUnknown status
Hvidovre Hospital
Coordinator of this site? Confirm its status
HvidovreDenmarkUnknown status
Slagelse Hospital
Coordinator of this site? Confirm its status
SlagelseDenmarkUnknown status
Hospital Clinic Barcelona
Coordinator of this site? Confirm its status
BarcelonaSpainUnknown status
Hospital Galdakao-Usansolo
Coordinator of this site? Confirm its status
GaldakaoSpainUnknown status
Hospital Alvaro Cunqueiro - Área Sanitária de Vigo
Coordinator of this site? Confirm its status
VigoSpainUnknown status
CHU Amiens-Picardie (Hopital Sud)
Coordinator of this site? Confirm its status
AmiensFranceUnknown status
CHU Estaing Clermont - Ferrand
Coordinator of this site? Confirm its status
Clermont-FerrandFranceUnknown status
Claude Huriez Hospital, Lille University
Coordinator of this site? Confirm its status
LilleFranceUnknown status
Hull University Teaching Hospitals NHS Trust
Coordinator of this site? Confirm its status
HullUnited KingdomUnknown status
St Mark's Hospital
Coordinator of this site? Confirm its status
LondonUnited KingdomUnknown status
Azienda Ospedaliera di Padova
Coordinator of this site? Confirm its status
PadovaItalyUnknown status
Mater dei hospital
Coordinator of this site? Confirm its status
MsidaMaltaUnknown status
Hospital Garcia da Orta
Coordinator of this site? Confirm its status
AlmadaPortugalUnknown status
Instituto Português de Oncologia de Lisboa
Coordinator of this site? Confirm its status
LisbonPortugalUnknown status
Hospital Beatriz Ângelo
Coordinator of this site? Confirm its status
LouresPortugalUnknown status
Algomed Policlinic
Coordinator of this site? Confirm its status
TimișoaraRomaniaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.