NCT05420233Active, not recruiting
The CROCO Study: CROhn's Disease COhort Study
Source: ClinicalTrials.gov · Last updated 28 Jul 2026
Brief summary (registry, in English)
The investigators propose to create a prospective Crohn Disease cohort, where patients receiving the most up-to-date therapies with a treat-to-target strategy, will be closely followed to characterize the progression of Crohn Disease by measuring the Lémann Index over time. The goal of the CROCO Study - "Crohn's Disease Cohort Study" is to promote a greater understanding of the long-term evolution of Crohn Disease , to describe prospectively the impact of different therapeutic strategies and develop accurate predictors of bowel disease damage and disability.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 533 (actual)
- First submitted
- 25 May 2022
- Start date
- 1 Aug 2021
- Primary completion date
- Jul 2030
- Lead sponsor
- GLSMED Learning Health S.A.
- Diseases
- Crohn's disease
- NCT number
- NCT05420233
What you commit to
- Study type: Interventional
- Participants enrolled: 533
- From 1 Aug 2021 to the primary completion date, Jul 2030
- 19 sites in 11 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Refusal or medical conditions (e.g. Glomerular filtration rate \< 30 mL/min) preventing cross-sectional imaging during follow-up;
Age
- Severe underlying medical disorder with an anticipated life expectancy \< 2 years;
Other
- Patients unwilling or unable to provide informed, written consent;
- Uncertain CD diagnosis;
- Pregnancy (if it is impossible to implement the MRE at one year) or any other reason that makes resonance not feasible throughout the study (eg claustrophobia).
Who the study is looking for
- To be eligible all of the following criteria must be met:
- Diagnosis of CD (according to ECCO guidelines) established within the past 12 months;
- Patients able to understand the information provided to them and to give written informed consent for the study;
- Male or female, age \> 18 years.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (19)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital CHU of Liège Coordinator of this site? Confirm its status | Liège | Belgium | Unknown status |
| American Gastroenterology Center Coordinator of this site? Confirm its status | Stróvolos | Cyprus | Unknown status |
| IBD Clinical and Research Clinic, ISCARE Coordinator of this site? Confirm its status | Prague | Czechia | Unknown status |
| Hvidovre Hospital Coordinator of this site? Confirm its status | Hvidovre | Denmark | Unknown status |
| Slagelse Hospital Coordinator of this site? Confirm its status | Slagelse | Denmark | Unknown status |
| Hospital Clinic Barcelona Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital Galdakao-Usansolo Coordinator of this site? Confirm its status | Galdakao | Spain | Unknown status |
| Hospital Alvaro Cunqueiro - Área Sanitária de Vigo Coordinator of this site? Confirm its status | Vigo | Spain | Unknown status |
| CHU Amiens-Picardie (Hopital Sud) Coordinator of this site? Confirm its status | Amiens | France | Unknown status |
| CHU Estaing Clermont - Ferrand Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| Claude Huriez Hospital, Lille University Coordinator of this site? Confirm its status | Lille | France | Unknown status |
| Hull University Teaching Hospitals NHS Trust Coordinator of this site? Confirm its status | Hull | United Kingdom | Unknown status |
| St Mark's Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Azienda Ospedaliera di Padova Coordinator of this site? Confirm its status | Padova | Italy | Unknown status |
| Mater dei hospital Coordinator of this site? Confirm its status | Msida | Malta | Unknown status |
| Hospital Garcia da Orta Coordinator of this site? Confirm its status | Almada | Portugal | Unknown status |
| Instituto Português de Oncologia de Lisboa Coordinator of this site? Confirm its status | Lisbon | Portugal | Unknown status |
| Hospital Beatriz Ângelo Coordinator of this site? Confirm its status | Loures | Portugal | Unknown status |
| Algomed Policlinic Coordinator of this site? Confirm its status | Timișoara | Romania | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.