Nerve Stimulation Guided Kidney Nerve Procedure for Uncontrolled High Blood Pressure
Tests a nerve stimulation guided kidney nerve procedure in adults with hard-to-control high blood pressure.
Plain-language title generated from the registry record
Registry title: Renal Nerve Stimulation in Uncontrolled Hypertensive Patients Undergoing Renal Denervation
Key facts
- Where
- Taipei, TaiwanSee the site
- Phase
- Phase 4
Where in Taiwan
- National Taiwan University HospitalTaipei, TaiwanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Taiwan University Hospital
- Trial code
- NCT05421767
- Record updated
- 16 June 2022
- Original description
Study design: Investigator initiated, single center The study is aimedRead full original descriptionShow less
National Tawan University Hospital
Study design: Investigator initiated, single center The study is aimed
1) To investigate the blood pressure (BP) change to renal nerve stimulation(RNS), and subsequently perform a renal denervation(RDN) procedure
1) to verify the cutoff value (RNS-induced systolic BP change <20 mmHg in post-RDN patients) could be a useful clinical endpoint in RDN therapy, and test the hypothesis that intense RDN could improve the efficacy of RDN.
Inclusion: Patients with hypertension (HTN), including; 24-hour ambulatory blood pressure >130/ 80 mmHg; Age 20-80 years; Glomerular filtration rate >45 mL/min.
Exclusion: Unsuitable renal artery anatomy computed tomographic angiography (main renal artery lumen diameter ≤3 mm or a total length <20 mm of the main arteries); untreated secondary HTN, including hyperaldosteronism, pheochromocytoma, renal artery stenosis(>50% stenosis).