Tests MINIject implant with cataract surgery for glaucoma and cataract
Tests a MINIject eye implant with cataract surgery in adults with glaucoma.
Plain-language title generated from the registry record
Registry title: MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract
Key facts
- Where
- Colchester and Edinburgh, United KingdomSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with primary open-angle glaucoma that eye drops do not control well, who also have a cataract that can be operated on. The MINIject implant is placed during cataract surgery.
- Age
- 40 years or older
- Sex
- Men and women
- Disease stage
- Primary open-angle glaucoma in the study eye, plus an age-related cataract that can be removed with phacoemulsification surgery and an intraocular lens implant.
- Earlier treatment
- Glaucoma not well controlled with at least one eye-pressure-lowering eye drop, unless the person is allergic to or cannot tolerate the medication.
Main reasons for not taking part
- Known or suspected allergy to medical silicone
- Allergy to fluorescein
- Silicone oil in the study eye
- Under tutorship or trusteeship
- Unable to give personal informed consent
Read by machine on 12 November 2026.
Where in United Kingdom
- East Suffolk and North Essex NHS Foundation Trust - Colchester General HospitalColchester, United KingdomNo longer taking part
- Princess Alexandra Eye PavilionEdinburgh, United KingdomNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- iSTAR Medical
- Trial code
- NCT05432245
- Record updated
- 28 February 2025
- Original description
The study will assess safety and performance of MINIject implant in patients with open-angle glaucoma uncontrolled by topical hypotensive medications in conjunction with cataract surgery.Read full original descriptionShow less
A Prospective, Open, Multicenter Clinical Trial Evaluating the Efficacy and Safety of MINIject Combined With Cataract Surgery in Patients With POAG Uncontrolled by Topical Hypotensive Medications and Operable Age-related Cataract Diagnosis
The study will assess safety and performance of MINIject implant in patients with open-angle glaucoma uncontrolled by topical hypotensive medications in conjunction with cataract surgery.
Inclusion: Diagnosis of primary open angle glaucoma (POAG) in the study eye; Operable age-related cataract eligible for phacoemulsification surgery with Intraocular Lens (IOL) implantation; Glaucoma not adequately controlled with at least one topical hypotensive medication(s), unless the patient has an allergy / intolerance to a medication; Patient must provide written informed consent to participate.
Exclusion: Known or suspected allergy or hypersensitivity to medical silicone; Allergy to fluorescein; Patient has a condition such that his / her ability to provide personal informed consent is compromised; Presence of silicone oil in the study eye; Individuals under tutorship or trusteeship.