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Tests electronic alerts to prompt heart medicines for heart failure patients

Tests a computer alert telling doctors about guideline heart failure medicines patients are not taking.

Plain-language title generated from the registry record
Registry title: PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure at Inova

Key facts

Where
Falls Church, United StatesSee the site

Where in United States

  • Inova Health SystemFalls Church, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Inova Health Care Services
Trial code
NCT05433220
Record updated
13 July 2026
Original description
A randomized, single-blind intervention trial to test the comparative effectiveness of an electronic health record best practice advisory system that informs clinicians of guideline-indicated and FDA-approved heart failure medications currently not prescribed to their patients with heart failure versus usual care (no alert and how things are done currently). The purpose of the alert is to stimulate appropriate medication prescription for patients with heart failure and a reduced ejection fraction. This will be done across outpatient Inova clinics and at the five Inova hospitals.Read full original descriptionShow less

PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure (PROMPT-HF) at Inova

A randomized, single-blind intervention trial to test the comparative effectiveness of an electronic health record best practice advisory system that informs clinicians of guideline-indicated and FDA-approved heart failure medications currently not prescribed to their patients with heart failure versus usual care (no alert and how things are done currently). The purpose of the alert is to stimulate appropriate medication prescription for patients with heart failure and a reduced ejection fraction. This will be done across outpatient Inova clinics and at the five Inova hospitals.

Inclusion: Age>18 Years; Seen by a Cardiologist in an Inova clinic or Inova hospital setting; Left Ventricular Ejection Fraction ≤40%.

Exclusion: Already receiving maximally titrated doses of each of the four classes of evidence- based HFrEF medical therapy; Prior heart transplant; Opted out of EHR-based research; Hospice care.

ClinicalTrials.gov NCT05433220