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CT-guided marking of tiny liver tumors before surgery

Tests CT-guided marking of tiny liver cancers before surgical removal, in adults with cirrhosis.

Plain-language title generated from the registry record
Registry title: CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

Key facts

Where
Yangzhou, ChinaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with liver cirrhosis and a very small liver cancer (micro hepatocellular carcinoma) that is hard to see on some scans, before surgery.

Age
18 years or older
Sex
All sexes can join
Disease stage
Cirrhosis of the liver from any cause, with micro hepatocellular carcinoma smaller than 1cm (0.4 in) in diameter
Biomarker or test result
The lesion is not found on a preoperative CT plain scan or B-ultrasound, but can be seen on CT enhancement or MRI

Main reasons for not taking part

  • Child-Pugh grade C
  • Uncontrolled high blood pressure
  • Severe lung dysfunction
  • Severe heart dysfunction

Read by machine on 12 November 2026.

Where in China

  • Clinical Medical College, Yangzhou UniversityYangzhou, ChinaContact: Guo-Qing Jiang, MDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Northern Jiangsu People's Hospital
Trial code
NCT05433467
Record updated
13 August 2025
Original description
In this project, the preoperative anatomical location of micro hepatocellular carcinoma under the guidance of CT can provide guidance for accurate surgical resection. It may also shorten the operation time and reduce intraoperative bleeding.Read full original descriptionShow less

The Feasibility of CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

In this project, the preoperative anatomical location of micro hepatocellular carcinoma under the guidance of CT can provide guidance for accurate surgical resection. It may also shorten the operation time and reduce intraoperative bleeding.

Inclusion: Be at least 18 years old and give informed consent to participate in the study; A preoperative (clinical, radiological, or histological) diagnosis of cirrhosis of the liver due to any cause; micro hepatocellular carcinoma (diameter less than 1cm); Preoperative CT plain scan could not find the lesion, and preoperative B-ultrasound could not find the lesion; Preoperative CT enhancement or MRI can detect the lesion.

Exclusion: Uncontrolled Hypertension; Severe cardiac dysfunction; Child-Pugh grade C; Severe lung dysfunction.

ClinicalTrials.gov NCT05433467