Scanning Small Uncertain Lung Spots With a Newer PET Scanner
Tests a new PET/CT scan to check uncertain lung nodules in adults.
Plain-language title generated from the registry record
Registry title: Lung Nodule Detection Using Ultra-long FOV PET/CT
Key facts
- Where
- Groningen, NetherlandsSee the site
- Phase
- Phase 4
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a lung nodule of 6-15 mm found on a chest CT scan. They must be scheduled for a biopsy or surgery to remove the nodule.
- Age
- 18 Years to 100 Years
- Sex
- All sexes can join.
- Disease stage
- Unclear (indeterminate) lung nodule of 6-15 mm in size, confirmed on chest CT.
- Earlier treatment
- A routine 18F-FDG PET/CT scan must have been done. Radiation therapy to the lung nodule is not allowed. A gap of at least 2 weeks is needed between the PET scan and the last systemic anti-cancer therapy.
Main reasons for not taking part
- Claustrophobia (fear of closed spaces)
- Pregnant or breastfeeding
- Radiation therapy to the lung nodule
- Uncontrolled diabetes mellitus
- Any medical condition that could get in the way of the trial
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 100 years old?
Source: NCT05463913, who can take part
Where in Netherlands
- University Medical Center GroningenGroningen, NetherlandsContact: Adrienne H Brouwers, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University Medical Center Groningen
- Trial code
- NCT05463913
- Record updated
- 7 March 2025
- Original description
Indeterminate lung nodules (6-15mm) are frequent findings in patients undergoing chest CT scanning, but adequate follow-up imaging is currently not in place to facilitate early detection, diagnosis and decision making regarding treatment.Read full original descriptionShow less
Ultra-long Field-Of-View Positron Emission Tomography for Characterization of Indeterminate Lung Nodules: a Pilot Study Exploring Opportunities for Clinical Research
Indeterminate lung nodules (6-15mm) are frequent findings in patients undergoing chest CT scanning, but adequate follow-up imaging is currently not in place to facilitate early detection, diagnosis and decision making regarding treatment.
The introduction of long Field-Of-View PET/CT scanners could make a difference in this matter due to the substantial increase in sensitivity allowing optimal image quality. Whether this new technology could provide improved detection and follow-up of indeterminate lung nodules is what we aim to explore in this study.
Inclusion: able to give informed consent; signed informed consent; confirmed indeterminate lung nodule(s) of 6-15 mm in size on CT chest imaging; routine 18F-FDG PET/CT performed; scheduled for biopsy or resection of the lung nodules.
Exclusion: radiation therapy of the target lung nodule(s); interval of at least 2 weeks between PET scan and last date of systemic anti-cancer therapy to reduce false-negative uptake in lesions; uncontrolled diabetes mellitus; any medical condition potentially hampering conduction of the trial; claustrophobia; pregnant or breastfeeding.