Compares MRI scans with tissue results for bladder tumour staging
Tests whether MRI scans can judge how deep bladder tumours have grown, in adults.
Plain-language title generated from the registry record
Registry title: Tumor Staging T of Bladder Tumours: Correlation of MRI and Anatomopathologic Analysis
Key facts
- Where
- Clermont-Ferrand, FranceSee the site
Where in France
- CHU Clermont-FerrandClermont-Ferrand, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Clermont-Ferrand
- Trial code
- NCT05464576
- Record updated
- 16 September 2026
- Original description
Urinary bladder tumors with a frequency of 13000 new cases a year, have a heterogeneity in terms of survival according to the stage of local flooding.Read full original descriptionShow less
Tumor Staging T of Bladder Tumours: Correlation of MRI and Anatomopathologic Analysis.
Urinary bladder tumors with a frequency of 13000 new cases a year, have a heterogeneity in terms of survival according to the stage of local flooding.
This is an aggressive tumor because of the potential muscular infiltration. It seems important in this case (muscular invasion), to increase the global survival.
The anatomopathological analysis of the TURB (biopsy byTrans-Urethral Resection of the Bladder) is actually the gold standard for the pathology of bladder tumor.
No need an imaging to discuss about the small and non muscular invasive tumor. But in most cases, the use is to perform at last an ultrasound or a CT-Scan, specially for the invasive tumor.
A lot of studies show that CT SCAN. is not the best way of investigation for the bladder muscle invasion. However, as in the prostate cancer with the PIRADS Score, the MRI can be useful for the bladder, thanks to the sequence improvement to the machine.
The study from Panebianco 2018, starts to talk about the MRI in the urinary bladder cancer with new radiological terms. It creates a new score called VIRADS score (as the PIRADS score already used for the prostate cancer). But it is never compared with the results of the TURB.
Our study compares the results of the MRI pre operative versus the pathology results on prospective analysis.
Main objective : T tumoral score in urinary bladder tumor : MRI versus pathology results.
Secondary objectives : the contribution of diffusion weighted MRI in the bladder neoplasm.
Type of study : interventional study, prospective, mono centric, single arm, intent-to-treat
Inclusion: Patient, male or female, aged >18ans; Benefiting from Social Security; Urinary bladder tumour confirmed on cystoscopy and requiring a TURB; Understanding and reading French well; Ability to give informed consent.
Exclusion: MRI contraindication : pacemaker, heart valve, clips, stents, coils, non-MRI compatible defibrillators, neural or peripheral stimulator, cochlear implant, intraocular foreign body, claustrophobia; Allergy to gadolinium (contrast product necessary for carrying out the MRI), hypersensitivity to gadoteric acid or gadolinated contrast products, to meglumine; Suspicion of an infectious disease such as schistosomiasis (differential diagnosis); Participation refusal; Patient under guardianship, deprived of liberty, impaired understanding; Pregnant/breastfeeding woman; Patient presenting with macroscopic clotting hematuria on the day of the MRI.