Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?
Key facts
- Where
- Edmonton, CanadaSee the site
- Phase
- Early phase 1
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT05467215, who can take part
Where in Canada
- University of Alberta, Clinical Sciences BldgEdmonton, CanadaContact: Michelle BarnesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Alberta
- Trial code
- NCT05467215
- Record updated
- 11 September 2026
- Original description
This proof-of-principle study will determine if breathing an increased concentration of oxygen above the concentration in normal room air results in changes in the sensory and motor function in people with subacute or chronic, severe spinal cord injury (SCI).Read full original descriptionShow less
This proof-of-principle study will determine if breathing an increased concentration of oxygen above the concentration in normal room air results in changes in the sensory and motor function in people with subacute or chronic, severe spinal cord injury (SCI).
Inclusion: Individuals with traumatic SCI with onset ≥3 months prior,; Between 18 - 65 yr old,; ASIA Impairment Scale at discharge classified as A, B or C,; Injury level between C5 and T10,; Able to give informed, written consent.
Exclusion: Cardiac or cardiovascular disease,; Cancer,; Active urinary tract infection,; Signs of deep vein thrombosis in the legs,; Severe cognitive impairment,; Pulmonary dysfunction such as chronic obstructive pulmonary disease or acute respiratory infection,; Any condition which would be exacerbated by sitting or lying in one position for 2 hours, such as low back pain; Frequent uncontrolled autonomic dysreflexia,; Uncontrolled high blood pressure,; Active pressure sores,; Severe swelling of the feet and/or legs,; Pregnancy.