The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement
Key facts
- Who runs it
- Negovsky Reanimatology Research Institute
- Where
- Moscow, RussiaSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 220 people, planned
- Started
- 3 Feb 2024
- Expected to end
- 1 Jul 2028
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Single-shot adductor canal block
- Continuous femoral nerve block
- Record updated
- 15 April 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Age ≥ 18
- Planned primary total knee replacement
- Planned neuraxial anesthesia
- Written informed consent
Who cannot take part
- Urgent surgery
- Previously enrolled in this trial
- Known allergic reaction to anesthetics
- Confirmed localized infection at the puncture sites
- Parkinson's disease
- Planned revision total knee replacement
- Confirmed localized tumor at the puncture sites
- Peripheral neuropathy of the lower extremities
Where in Russia
- Clinical Hospital on YauzaMoscow, RussiaContact: Levan Berikashvili, PhDTaking people
About the trial
What the trial wants to find out
Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis. A well-known problem of TKR is a severe postoperative pain syndrome, which is observed in more than 50% of patients.
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Femoral nerve block (FNB) is the "gold standard" for continuous postoperative analgesia after total knee replacement, as it is effective in reducing the frequency of use of opioid analgetics and reduce the duration of hospitalization. At the same time, the negative effect of this method is the motor blockade of the quadriceps femoris muscle which leads to functional impairment and is associated with an increased risk of falling.
Adductor canal block (ACB) provides adequate analgesia comparable to femoral nerve block. Moreover, ACB doesn't affect the motor function of the quadriceps femoris muscle.
The possibility of enhanced recovery after total knee replacement is the reason to compare single-shot adductor canal block and continuous femoral nerve block.
The 2 groups in the trial
- Single-shot adductor canal blockTreatment being tested
- Continuous femoral nerve blockExisting treatment, for comparison
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement (AdORe - ACB)
- Record updated
- 15 April 2026