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Quality of life over time in people with diabetes and long-term Charcot foot

Follows adults with diabetes and Charcot foot to see what shapes quality of life.

Key facts

Who runs it
Centre Hospitalier Universitaire de Nīmes
Where
France17 sites in 1 countryChoose a country to see its sites
Trial code
Registry title
Factors Associated With an Evolution in the Quality of Life of Diabetic Patients With Chronic, Wound-free Charcot Foot
Status
Recruiting
People taking part
150 people, planned
Started
23 Jan 2023
Expected to end
22 Jan 2028
Type of study
Observational
Treatments tested
  • Filling in the SF-36, FAAM-F, PHQ-9, PHQ-2 and the simplified version of the EPICES score questionnaire
Record updated
23 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with diabetes who have long-lasting (chronic) Charcot foot without wounds. It follows their quality of life over 2 years using questionnaires.

Age
18 years and older
Sex
All sexes
Disease stage
Charcot foot (diabetic osteoarthropathy, damage to foot and ankle bones and joints) in its chronic stage, without wounds. People with type 1, type 2 or secondary diabetes can join.

Main reasons for not taking part

  • Charcot foot not caused by diabetes
  • Charcot foot in its acute (early, active) stage
  • A foot ulcer (open sore on the foot)
  • Being pregnant, giving birth or breastfeeding
  • Being under court protection, guardianship or trusteeship

The registry criteria, word for word

Show all 12 criteriaShow less

Who can take part

  • patients with Type 1 or 2 diabetes or secondary diabetes
  • patient hospitalized or consulting for osteoarthropathy in its chronic stage, without wounds
  • patients affiliated to or beneficiaries of a health insurance scheme
  • adult patients (≥18 years old)

Who cannot take part

  • patients with a foot ulcer
  • patients with non-diabetic osteoarthropathy of the nerves
  • patients with acute diabetic osteoarthropathy of the nerves
  • patients who have expressed opposition to participating in the study
  • patients in an exclusion period determined by another study
  • patients under court protection, guardianship or trusteeship
  • patients for whom it is impossible to give informed information
  • pregnant, parturient, or breastfeeding patients

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

Charcot foot, characterized by progressive destructive damage to bone, soft tissue and tendons, involving joint dislocation in the ankle and foot, is a complication of diabetes that is still poorly understood by patients and caregivers. The clinical signs are non-specific and it is therefore largely underestimated due to a delay in diagnosis/lack of diagnosis.This study will be on a prospective multicenter cohort of patients with chronic Charcot's foot in France to evaluate the evolution of quality of life at 2 years, as well as predictive factors in order to better identify subjects with the worst outcome among this population.

Read full original descriptionShow less

Our hypothesis is that, in patients with chronic Charcot foot, the deterioration in quality of life over time is primarily related to loss of foot and ankle functionality, foot and ankle deformity and the presence of foot wounds/comorbidities/severe diabetic complications.

Treatments tested

  • Filling in the SF-36, FAAM-F, PHQ-9, PHQ-2 and the simplified version of the EPICES score questionnaire

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Factors Associated With Quality of Life Outcomes in Diabetic Patients With Chronic Wound-free Charcot Foot
Plain-language title
Quality of life over time in people with diabetes and long-term Charcot footGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 15 November 2026.
Record updated
23 October 2026