The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma
Key facts
- Where
- Changsha and Shanghai, ChinaSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 14 and 75 years old?
Source: NCT05496582, who can take part
Where in China
- Xiangya Hospital Central South UniversityChangsha, ChinaTaking people
- Yueyang Hospital, Shanghai University of Traditional Chinese MedicineShanghai, ChinaNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai University of Traditional Chinese Medicine
- Trial code
- NCT05496582
- Record updated
- 8 May 2024
- Original description
Asthma is one of the most common chronic respiratory diseases. Previous study found a series of differentially expressed genes and proteins (transgelin-2, metallothionein-2, ezrin) in asthmatic rat. The aim of the study is to investigate the changes and associations of these gene with asthma in human.Read full original descriptionShow less
The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma: A Case-control Study
Asthma is one of the most common chronic respiratory diseases. Previous study found a series of differentially expressed genes and proteins (transgelin-2, metallothionein-2, ezrin) in asthmatic rat. The aim of the study is to investigate the changes and associations of these gene with asthma in human.
Inclusion: Males or females, aged 14-75 years; Patients with a definite diagnosis of bronchial asthma; The diagnosis of asthma according to the Global Initiative for Asthma (GINA), with positive bronchodilator responsiveness (reversibility) test; Healthy volunteers without respiratory symptoms such as cough, wheezing, chest tightness or dyspnea; Agree with all procedures in this trial by signing a written informed consent form.
Exclusion: Patients with chronic obstructive pulmonary disease or other airway disease; Complicated with other severe primary diseases (including hypertension, cancer, hyperthyroidism, bronchiectasia, cardiac insufficiency) and conditions that would prevent participation in the trial or put the participant at risk; Psychiatric history and neurological disorders can not work normally; Other conditions that the researcher considers inappropriate to participate in this study; Women who are known to be pregnant or breastfeeding; Not willing to participate.