Tests personalized music listening for apathy in Parkinson's disease
Tests whether personalized music listening can ease apathy in people with Parkinson's disease.
Plain-language title generated from the registry record
Registry title: Targeting Apathy With Music in Parkinson's Disease
Key facts
- Where
- Vancouver, CanadaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 85 years old?
Source: NCT05505019, who can take part
Where in Canada
- Djavad Mowafghian Centre for Brain HealthVancouver, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of British Columbia
- Trial code
- NCT05505019
- Record updated
- 23 March 2026
- Original description
Parkinson's Disease (PD) is often accompanied by non-motor symptoms that make treatment more difficult. One such symptom is apathy (lack of motivation and emotion). There are no treatments for apathy in PD, and this remains a major unmet need in PD patients. One possible way to target apathy in PD patients is listening to music, which has been shown to help improve apathy in older adults. Little work has explored the mechanism in which music targets apathy. Thus, the goal of this study is to understand how music listening can impact the brain towards decreasing apathy in PD patients.Read full original descriptionShow less
The Role of a Personalized Music Intervention Towards Alleviating Apathy in Parkinson's Disease
Parkinson's Disease (PD) is often accompanied by non-motor symptoms that make treatment more difficult. One such symptom is apathy (lack of motivation and emotion). There are no treatments for apathy in PD, and this remains a major unmet need in PD patients. One possible way to target apathy in PD patients is listening to music, which has been shown to help improve apathy in older adults. Little work has explored the mechanism in which music targets apathy. Thus, the goal of this study is to understand how music listening can impact the brain towards decreasing apathy in PD patients.
Inclusion: Clinical diagnosis of Parkinson's Disease following MDS Parkinson's disease criteria.
Exclusion: Participants with atypical Parkinsonism (eg. Progressive supranuclear palsy, multiple system atrophy, drug induced, etc.); Participants who have gone through specific injuries/brain surgery (eg. an injury where a piece of metal lodged in the eye or orbit); Epilepsy; Other neurological disease/complications (eg. myopathy, stroke, brain lesion, MS); Significant cognitive impairment (MoCa <21); Participants with metal/medical implants, including any of the following: artificial heart valve, brain aneurysm clip, electrical stimulators, ear or eye implant, implanted drug infusion pump, coil, catheter, or filter in any blood vessel, orthopedic hardware such as artificial joint, plate, and/or screws, other metallic prostheses, shrapnel, bullets, or other metal fragments, surgery or tattoos, including tattooed eyeliner, in the last six weeks, cardiac pacemaker, wires or defibrillator, or ferromagnetic aneurysm clip); Moderate depression (Beck's Depression Inventory >20); Severe/multiple head trauma(s).