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Light Therapy and Occupational Therapy for Fatigue in Genitourinary Cancers

Tests light and occupational therapy for cancer fatigue in genitourinary cancers.

Plain-language title generated from the registry record
Registry title: Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

Key facts

Where
Duarte, United StatesSee the site

Where in United States

  • City of Hope Medical CenterDuarte, United StatesTaking people

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Trial details

Who runs it
City of Hope Medical Center
Trial code
NCT05519878
Record updated
19 October 2026
Original description
This clinical trial evaluates light therapy and occupational therapy in improving cancer related fatigue (CRF) patients with genitourinary cancers. Light therapy is a non-pharmacological and evidence-based intervention for managing fatigue in cancer patients. The use of light therapy can provide a low burden, inexpensive, and easy to disseminate intervention approach that can potentially have a larger impact on CRF. In addition, occupational therapy is a standard, but often underutilized, component of the multi-disciplinary approach to cancer care. Using the combination of light therapy and occupational therapy may be effective in CRF management.Read full original descriptionShow less

Assessing Efficacy of a Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

This clinical trial evaluates light therapy and occupational therapy in improving cancer related fatigue (CRF) patients with genitourinary cancers. Light therapy is a non-pharmacological and evidence-based intervention for managing fatigue in cancer patients. The use of light therapy can provide a low burden, inexpensive, and easy to disseminate intervention approach that can potentially have a larger impact on CRF. In addition, occupational therapy is a standard, but often underutilized, component of the multi-disciplinary approach to cancer care. Using the combination of light therapy and occupational therapy may be effective in CRF management.

Inclusion: Aged 18 and over; Sufficiently fluent in English; On active treatment receiving systemic therapy (e.g., chemotherapy, immunotherapy, hormonal therapy, etc.) or radiotherapy; Patients with diagnosis of a genitourinary (GU) cancer (e.g., prostate, kidney, and bladder cancer) who have grade 1 or 2 fatigue based on physician assessment at the time of study entry; Clinician assessed prognosis of greater than or equal to six months; Willing and independently able to provide consent; Receive a pre-screen FACIT-Fatigue score of less than or equal to 30.

Exclusion: Previous use of light therapy to alleviate fatigue or depressive symptoms; Currently recovering from previous eye surgery within the past 6 months that causes eye irritation; Severe sleep disorders (e.g. narcolepsy); Eye Diseases which limit the ability of light to be processed (e.g. untreated cataracts, severe glaucoma, macular degeneration, blindness, pupil dilation problems or other retinal disorder); Severe psychological impairment (e.g., bipolar disorder or manic episodes); Secondary cancer diagnosis within the past 5 years; Sensitivity to light, epilepsy, or a history of seizures; Current employment in night shift work; Plans to travel across meridians during treatment; Pregnancy.

ClinicalTrials.gov NCT05519878