Cushing's Syndrome Before and After Treatment (CORRECT)
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Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Aarhus
- Trial code
- NCT05521529
- Record updated
- 4 April 2025
- Original description
The purpose of this study is to prospectively study patients with Cushing's syndrome before and after treatment, with a special emphasis on physical function, quality of life, and circadian rhythms.Read full original descriptionShow less
Effects of CORtisol Excess and REmission in Cushing's Syndrome Over Time (CORRECT): A Prospective Non-interventional Cohort Study
The purpose of this study is to prospectively study patients with Cushing's syndrome before and after treatment, with a special emphasis on physical function, quality of life, and circadian rhythms.
The hypotheses are:
* Cushing's syndrome negatively impacts health-related quality of life (HRQoL) and physical functioning * Cushing's syndrome is associated with altered circadian rhythms at the whole body level and in peripheral target tissues. * These complications partially reverse following disease control.
Inclusion: New (≤ 2 months) diagnosis of Cushing's syndrome (CS) of endogenous etiology:; ACTH-dependent CS; ACTH-independent CS; Age >18 years; Written informed consent.
Exclusion: Active cancer; Iatrogenic or malignant cause of CS such as adrenocortical carcinoma; Chronic heart failure (New York Heart Association class IV); Liver disease in the form of cirrhosis; Chronic kidney disease Chronic Kidney Disease stage ≥3 (eGFR >30 ml/min); Deemed unable to complete the study safely by investigator.