Comparing Sedation Methods During Stroke Clot Removal Treatment
Compares sedation with general anesthesia in adults with vertebrobasilar stroke undergoing endovascular treatment.
Plain-language title generated from the registry record
Registry title: Mode of Sedation During Endovascular Treatment of Vertebrobasilar Stroke
Key facts
- Where
- Heidelberg, GermanySee the site
Where in Germany
- Department of Neurology, University Hospital HeidelbergHeidelberg, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital Heidelberg
- Trial code
- NCT05525325
- Record updated
- 30 April 2026
- Original description
Optimal anesthetic mode is not established for patients with vertebrobasilar stroke undergoing endovascular treatment. We want to investigate whether a procedural sedation mode approach is feasible compared to general anesthesiaRead full original descriptionShow less
Mode of Sedation During Endovascular Treatment of Vertebrobasilar Stroke
Optimal anesthetic mode is not established for patients with vertebrobasilar stroke undergoing endovascular treatment. We want to investigate whether a procedural sedation mode approach is feasible compared to general anesthesia
Inclusion: Decision for thrombectomy according to local protocol for acute recanalizing stroke treatment; Age 18 years or older, either sex; National Institutes of Health Stroke Scale (NIHSS) ≥ 4; Acute ischemic stroke in the posterior circulation with isolated or combined occlusion of vertebral artery (VA) and basilar artery (BA); Informed consent by the patient him-/herself or his/her legal representative obtainable within 72 h of treatment (deferred consenting procedure).
Exclusion: Intracerebral hemorrhage; Severe hemodynamic instability (e.g. due to decompensated cardiac insufficiency); Coma on admission (Glasgow Coma Scale ≤ 8); Severe respiratory instability, loss of airway protective reflexes or vomiting on admission, where primary intubation and general anesthesia is deemed necessary; Intubated state before randomization.