NCT05526092Active, not recruiting
OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals
OAT-GUT-BRAIN: Comprehensive Health Effects of Long-term Consumption of Oats in Metabolically Challenged Volunteers - Gut-mediated Metabolomics and Vitality
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
The overall objective of this research entity is to reveal the comprehensive health impact of oats in metabolically challenged individuals in a 6-week intervention, compared to that of rice. This is achieved by investigation of the lipids, short-chain fatty acids, inflammation markers and antioxidant status from plasma, fecal microbiome, and plasma metabolome. Additionally the effect of the 6-week diet on postprandial glycemia and postprandial satiety and vitality are investigated.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 72 (actual)
- First submitted
- 26 Aug 2022
- Start date
- 12 Sept 2022
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- University of Turku
- NCT number
- NCT05526092
What you commit to
- Study type: Interventional
- Participants enrolled: 72
- From 12 Sept 2022 to the primary completion date, 31 Dec 2023
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent course of antibiotics (less than 3 months prior to the study)
Other illness
- Regular medication that can affect the research outcomes (balanced medication for hypertension, hypo-/hyperthyroidism, hormone replacement therapy, and inhaled medicines allowed)
Other
- Pregnancy or lactation
- Heavy smoking
Who the study is looking for
- Commits to follow the instructed low-gluten diet for 6 weeks
- 30 - 68 years of age
- BMI \> 25 kg/m\^2
- High cholesterol (without medication) characterized as total cholesterol \> 5 mmol/l, AND either LDL \> 3 mmol/l OR HDL (men/women) \< 1.0/1.2 mmol/l AND/OR Hypertension (systolic \> 140 mmHg or diastolic \> 90 mmHg).
Age in the registry: 30 years to 68 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institute of Public Health and Clinical Nutrition, University of Eastern Finland Coordinator of this site? Confirm its status | Kuopio | Finland | Unknown status |
| Food Sciences, Department of Life Technologies, University of Turku Coordinator of this site? Confirm its status | Turku | Finland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.