Studies whether a stroke clot-removal device, Tigertriever, is linked to thinking ability
Observes adults with stroke treated by Tigertriever to see how it relates to thinking.
Plain-language title generated from the registry record
Registry title: Cognition and Imaging With Tigertriever
Key facts
- Where
- Grand Rapids, Los Angeles, New York, Orange, Philadelphia, and The Bronx, United StatesSee the 6 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05531461, who can take part
Where in United States
- Corewell Health Research InstituteGrand Rapids, United StatesTaking people
- University of CaliforniaLos Angeles, United StatesTaking people
- Westchester Medical CenterNew York, United StatesTaking people
- University of California IrvineOrange, United StatesTaking people
- The Hospital of the University of PennsylvaniaPhiladelphia, United StatesTaking people
- Montefiore Medical Center The University Hospital for Albert Einstein College of MedicineThe Bronx, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Rapid Medical
- Trial code
- NCT05531461
- Record updated
- 9 October 2026
- Original description
The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.Read full original descriptionShow less
COGNITIVE Study- Cognition and Imaging With Tigertriever
The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.
Inclusion: Patients admitted with large vessel occlusion (LVO) and treated with the Tigertriever, as indicated per the approved IFU; Tigertriever was used as the first line treatment in the target vessel; A signed informed consent; Age 18-75 years (inclusive); No known significant pre-stroke disability (pre-stroke mRS 0 or 1).
Exclusion: Use of any other IA recanalization device prior to the Tigertriever in the target vessel, including aspiration catheter; Prior hemorrhage, stroke, thrombolysis, and/or endovascular therapy in the last 3 months; Evidence of acute brain hemorrhage on CT and/or MRI at admission; Pre-stroke diagnosed dementia and/or prescribed cholinesterase inhibitors; Pre-stroke diagnosed and/or currently treated major depression; Pre-stroke learning or intellectual disability; Probable cerebral amyloid angiopathy; Anticipated inability to obtain 6-month follow-up assessments; -.