Frontlight ResearchEarly access
WithdrawnNo phase
C-arm Cone Beam CTP Guided Cerebrovascular Interventions
Key facts
- Who runs it
- University of Wisconsin, Madison
- Where
- Madison, United StatesSee the site
- Trial code
- Status
- Withdrawn
- Started
- Mar 2025
- Ended
- Mar 2026
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- C-Arm Cone Beam Computed Tomography
- Multi-detector Computed Tomography
- Record updated
- 4 April 2025
- Why it stopped
- There is now a commercially available product, the evidence from this study is no longer required to justify adoption of perfusion imaging in the angio suite.
Who can take part
- Age
- 18 years to 99 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Patients with acute ischemic stroke presenting within 24 hours of onset
- Patients that present with a large artery occlusion
- Adults 18 years of age or older
- Patients of childbearing potential must not be pregnant
- National Institutes of Health Stroke Scale (NIHSS) of <8
- No severe co-morbidities
Who cannot take part
- History of severe renal disease (e.g. stage 4-5)
- History of renal transplant
- Patients that are pregnant
Where in United States
- University of Wisconsin - MadisonMadison, United States
About the trial
What the trial wants to find out
The study objective for the Phase 2 of this research is to demonstrate and confirm the substantial time savings that can be obtained using cone beam computed tomography (CB-CT) for both complete image acquisition and rapid image reconstruction in a Direct to Angio paradigm (One Stop Shop) for selected acute ischemic stroke (AIS) patients.
The 2 groups in the trial
- C-ARM CBCTTreatment being tested
A C-arm CBCT evaluation with SMART RECON novel software for the rapid assessment of time-resolved CT angiogram and CT perfusion.
Treatment: C-Arm Cone Beam Computed Tomography
- MD-CTExisting treatment, for comparison
An evaluation with conventional, standard of care, multi-detector CT (MD-CT)
Treatment: Multi-detector Computed Tomography
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- C-arm Cone Beam CTP Guided Cerebrovascular Interventions: Evaluating Predictability and Accuracy for the Treatment of Acute Cerebral Ischemia in the Angiography Suite
- Record updated
- 4 April 2025