Brain scans of urination control in people with a sigmoid neobladder
Uses brain scans to study urge and control of urination in adults.
Plain-language title generated from the registry record
Registry title: The Supraspinal Control of Lower Urinary Tract Function in Patients With Orthotopic Sigmoid Neobladder.
Key facts
- Where
- Guangzhou, ChinaSee the site
Where in China
- Zhujiang Hospital of Southern Medical UniversityGuangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Zhujiang Hospital
- Trial code
- NCT05558111
- Record updated
- 8 October 2026
- Original description
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain activity of lower urinary tract function in neobladder patients is still unclear.The aim of this study is to explore the brain activity of urination intention and self-controlled urination behavior in patients with orthotopic sigmoid neobladder by task-state functional magnetic resonance imaging (fMRI).Read full original descriptionShow less
Neuroimaging Study of Supraspinal Control of Lower Urinary Tract Function in Patients With Orthotopic Sigmoid Neobladder.
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain activity of lower urinary tract function in neobladder patients is still unclear.The aim of this study is to explore the brain activity of urination intention and self-controlled urination behavior in patients with orthotopic sigmoid neobladder by task-state functional magnetic resonance imaging (fMRI).
Inclusion: Being right-handed; 3 months or more after operation; No contraindications to fMIR examination; Voluntarily sign informed consent.
Exclusion: Claustrophobia or carrying metal implants that are not suitable for fMRI examination; History of bladder radiotherapy; History of prostate cancer; Suffering from diseases affecting abdominal pressure; History of abnormal brain anatomy, craniocerebral surgery, craniocerebral tumor, and craniocerebral radiotherapy; History of mental disorders, Parkinson's disease, Alzheimer's disease, epilepsy, cerebral infarction, cerebral hemorrhage; Diseases affecting lower urinary tract function (such as spinal cord injury, diabetic peripheral neuropathy, etc.); Other conditions that were not suitable for inclusion according to the investigator's judgment; Urethral stricture; Refusing to sign the informed consent form for clinical projects.