Brain Imaging Patterns Studied With Stimulation in Stroke Survivors
Tests brain stimulation with a weak current in adults with stroke, using brain scans.
Plain-language title generated from the registry record
Registry title: Network Properties As Biomarkers for Non-Invasive Brain Stimulation (NIBS) After Stroke
Key facts
- Where
- Hamburg, GermanySee the site
Where in Germany
- University Medical Center Hamburg-Eppendorf, Dept. of NeurologyHamburg, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universitätsklinikum Hamburg-Eppendorf
- Trial code
- NCT05560724
- Record updated
- 17 December 2024
- Original description
The present study will evaluate the potential of cortico-cerebellar network properties derived from neuroimaging in a group of chronic stroke patients to explain inter-subject variability in responsiveness to transcranial direct current stimulation (tDCS) targeting the cortico-spinal and cortico-cerebellar network.Read full original descriptionShow less
Evaluation of Cortico-Cerebellar Network Properties As Biomarkers for the Responsiveness to Cortico-Cerebellar Brain Stimulation in Stroke Patients
The present study will evaluate the potential of cortico-cerebellar network properties derived from neuroimaging in a group of chronic stroke patients to explain inter-subject variability in responsiveness to transcranial direct current stimulation (tDCS) targeting the cortico-spinal and cortico-cerebellar network.
Inclusion: patients after first-ever clinical ischemic stroke in the early (>3 month) or later chronic (>6 months) stage of recovery; persistent motor deficit of the upper extremity; stroke location: supratentorial; age > 18 years; written informed consent obtained.
Exclusion: known epilepsy, previous epileptic seizure; electric implants such as brain stimulator; medical history suggesting more than one previous stroke; any active drug and alcohol abuse; severe polyneuropathy and peripheral ischemic vascular diseases; only if they critically influence sensorimotor function of the upper limb; any active and severe psychiatric disease (such as psychosis); uncontrolled other medical problems (cardiovascular diseases, instable arrhythmia, arthritis); contraindication against MRI \& tDCS; severe cognitive deficits (mini mental state examination, MMSE ≤ 23).